Goosen TC[au] - Search Results

Year	Number of Results
2000	1
2001	1
2002	3
2003	1
2004	3
2005	1
2006	2
2007	2
2009	1
2010	2
2011	2
2012	5
2013	11
2014	4
2015	2
2016	2
2017	3
2018	6
2019	1
2020	5
2021	4
2022	4
2023	0

1

Intestinal targeting of drugs: rational design approaches and challenges.

Filipski KJ, Varma MV, El-Kattan AF, Ambler CM, Ruggeri RB, Goosen TC, Cameron KO. Filipski KJ, et al. Among authors: goosen tc. Curr Top Med Chem. 2013;13(7):776-802. doi: 10.2174/1568026611313070002. Curr Top Med Chem. 2013. PMID: 23578023 Review.

2

Model-based approaches to predict drug-drug interactions associated with hepatic uptake transporters: preclinical, clinical and beyond.

Barton HA, Lai Y, Goosen TC, Jones HM, El-Kattan AF, Gosset JR, Lin J, Varma MV. Barton HA, et al. Among authors: goosen tc. Expert Opin Drug Metab Toxicol. 2013 Apr;9(4):459-72. doi: 10.1517/17425255.2013.759210. Epub 2013 Jan 21. Expert Opin Drug Metab Toxicol. 2013. PMID: 23331046 Review.

3

Evidence-based strategies for the characterisation of human drug and chemical glucuronidation in vitro and UDP-glucuronosyltransferase reaction phenotyping.

Miners JO, Rowland A, Novak JJ, Lapham K, Goosen TC. Miners JO, et al. Among authors: goosen tc. Pharmacol Ther. 2021 Feb;218:107689. doi: 10.1016/j.pharmthera.2020.107689. Epub 2020 Sep 25. Pharmacol Ther. 2021. PMID: 32980440 Review.

4

An improved method for cytochrome p450 reaction phenotyping using a sequential qualitative-then-quantitative approach.

Doran AC, Dantonio AL, Gualtieri GM, Balesano A, Landers C, Burchett W, Goosen TC, Obach RS. Doran AC, et al. Among authors: goosen tc. Drug Metab Dispos. 2022 Jul 1:DMD-AR-2022-000883. doi: 10.1124/dmd.122.000883. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35777845 Free article.

5

The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans.

Bauman JN, Doran AC, King-Ahmad A, Sharma R, Walker GS, Lin J, Lin TH, Telliez JB, Tripathy S, Goosen TC, Banfield C, Malhotra BK, Dowty ME. Bauman JN, et al. Among authors: goosen tc. Drug Metab Dispos. 2022 Aug;50(8):1106-1118. doi: 10.1124/dmd.122.000829. Epub 2022 Jun 14. Drug Metab Dispos. 2022. PMID: 35701182

6

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios.

Williams JA, Hyland R, Jones BC, Smith DA, Hurst S, Goosen TC, Peterkin V, Koup JR, Ball SE. Williams JA, et al. Among authors: goosen tc. Drug Metab Dispos. 2004 Nov;32(11):1201-8. doi: 10.1124/dmd.104.000794. Epub 2004 Aug 10. Drug Metab Dispos. 2004. PMID: 15304429 Review.

7

Investigation of CYP3A induction by PF-05251749 in early clinical development: comparison of linear slope physiologically based pharmacokinetic prediction and biomarker response.

Lin J, Gaudreault F, Johnson N, Lin Z, Nouri P, Goosen TC, Sawant-Basak A. Lin J, et al. Among authors: goosen tc. Clin Transl Sci. 2022 Sep;15(9):2184-2194. doi: 10.1111/cts.13352. Epub 2022 Jul 2. Clin Transl Sci. 2022. PMID: 35730131 Free PMC article.

8

In Vitro Kinetic Characterization of Axitinib Metabolism.

Zientek MA, Goosen TC, Tseng E, Lin J, Bauman JN, Walker GS, Kang P, Jiang Y, Freiwald S, Neul D, Smith BJ. Zientek MA, et al. Among authors: goosen tc. Drug Metab Dispos. 2016 Jan;44(1):102-14. doi: 10.1124/dmd.115.065615. Epub 2015 Oct 28. Drug Metab Dispos. 2016. PMID: 26512042

9

Physiologically-Based Pharmacokinetic Modeling of the Drug-Drug Interaction of the UGT Substrate Ertugliflozin Following Co-Administration with the UGT Inhibitor Mefenamic Acid.

Callegari E, Lin J, Tse S, Goosen TC, Sahasrabudhe V. Callegari E, et al. Among authors: goosen tc. CPT Pharmacometrics Syst Pharmacol. 2021 Feb;10(2):127-136. doi: 10.1002/psp4.12581. Epub 2020 Dec 30. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33314761 Free PMC article. Clinical Trial.

10

Defining the Selectivity of Chemical Inhibitors Used for Cytochrome P450 Reaction Phenotyping: Overcoming Selectivity Limitations with a Six-Parameter Inhibition Curve-Fitting Approach.

Doran AC, Burchett W, Landers C, Gualtieri GM, Balesano A, Eng H, Dantonio AL, Goosen TC, Obach RS. Doran AC, et al. Among authors: goosen tc. Drug Metab Dispos. 2022 Jul 1:DMD-AR-2022-000884. doi: 10.1124/dmd.122.000884. Online ahead of print. Drug Metab Dispos. 2022. PMID: 35777846 Free article.

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