Gorycki PD[au] - Search Results

Year	Number of Results
1989	1
1990	1
1994	1
1998	3
1999	1
2002	1
2004	2
2006	1
2007	1
2011	3
2012	1
2013	2
2014	1
2022	0

1

Investigations of hydrazine cleavage of eltrombopag in humans.

Deng Y, Rogers M, Sychterz C, Talley K, Qian Y, Bershas D, Ho M, Shi W, Chen EP, Serabjit-Singh C, Gorycki PD. Deng Y, et al. Among authors: gorycki pd. Drug Metab Dispos. 2011 Sep;39(9):1747-54. doi: 10.1124/dmd.111.040188. Epub 2011 Jun 6. Drug Metab Dispos. 2011. PMID: 21646438

2

Metabolism of [(14)C]GSK977779 in rats and its implication with the observed covalent binding.

Tsalta CD, Madatian A, Schubert EM, Xia F, Hardesty WM, Deng Y, Seymour JL, Gorycki PD. Tsalta CD, et al. Among authors: gorycki pd. Drug Metab Dispos. 2011 Sep;39(9):1620-32. doi: 10.1124/dmd.110.036467. Epub 2011 May 31. Drug Metab Dispos. 2011. PMID: 21628498

3

Bioavailability, metabolism and disposition of oral pazopanib in patients with advanced cancer.

Deng Y, Sychterz C, Suttle AB, Dar MM, Bershas D, Negash K, Qian Y, Chen EP, Gorycki PD, Ho MY. Deng Y, et al. Among authors: gorycki pd. Xenobiotica. 2013 May;43(5):443-53. doi: 10.3109/00498254.2012.734642. Epub 2012 Nov 16. Xenobiotica. 2013. PMID: 23548165 Clinical Trial.

4

Present status of the application of cryopreserved hepatocytes in the evaluation of xenobiotics: consensus of an international expert panel.

Li AP, Gorycki PD, Hengstler JG, Kedderis GL, Koebe HG, Rahmani R, de Sousas G, Silva JM, Skett P. Li AP, et al. Among authors: gorycki pd. Chem Biol Interact. 1999 Jun 1;121(1):117-23. doi: 10.1016/s0009-2797(99)00081-2. Chem Biol Interact. 1999. PMID: 10418974 Review.

5

The oxidation of tetrasubstituted alkenes by cytochrome P450.

Gorycki PD, Macdonald TL. Gorycki PD, et al. Chem Res Toxicol. 1994 Nov-Dec;7(6):745-51. doi: 10.1021/tx00042a006. Chem Res Toxicol. 1994. PMID: 7696528

6

Metabolism and disposition of eltrombopag, an oral, nonpeptide thrombopoietin receptor agonist, in healthy human subjects.

Deng Y, Madatian A, Wire MB, Bowen C, Park JW, Williams D, Peng B, Schubert E, Gorycki F, Levy M, Gorycki PD. Deng Y, et al. Among authors: gorycki pd. Drug Metab Dispos. 2011 Sep;39(9):1734-46. doi: 10.1124/dmd.111.040170. Epub 2011 Jun 6. Drug Metab Dispos. 2011. PMID: 21646437 Clinical Trial.

7

Discovery of potent and orally bioavailable N,N'-diarylurea antagonists for the CXCR2 chemokine receptor.

Jin Q, Nie H, McCleland BW, Widdowson KL, Palovich MR, Elliott JD, Goodman RM, Burman M, Sarau HM, Ward KW, Nord M, Orr BM, Gorycki PD, Busch-Petersen J. Jin Q, et al. Among authors: gorycki pd. Bioorg Med Chem Lett. 2004 Sep 6;14(17):4375-8. doi: 10.1016/j.bmcl.2004.06.097. Bioorg Med Chem Lett. 2004. PMID: 15357956

8

Investigation of metabolism and disposition of GSK1322322, a peptidase deformylase inhibitor, in healthy humans using the entero-test for biliary sampling.

Mamaril-Fishman D, Zhu J, Lin M, Felgate C, Jones L, Stump P, Pierre E, Bowen C, Naderer O, Dumont E, Patel P, Gorycki PD, Wen B, Chen L, Deng Y. Mamaril-Fishman D, et al. Among authors: gorycki pd. Drug Metab Dispos. 2014 Aug;42(8):1314-25. doi: 10.1124/dmd.114.058420. Epub 2014 May 28. Drug Metab Dispos. 2014. PMID: 24872378 Clinical Trial.

9

Metabolism and disposition of oral dabrafenib in cancer patients: proposed participation of aryl nitrogen in carbon-carbon bond cleavage via decarboxylation following enzymatic oxidation.

Bershas DA, Ouellet D, Mamaril-Fishman DB, Nebot N, Carson SW, Blackman SC, Morrison RA, Adams JL, Jurusik KE, Knecht DM, Gorycki PD, Richards-Peterson LE. Bershas DA, et al. Among authors: gorycki pd. Drug Metab Dispos. 2013 Dec;41(12):2215-24. doi: 10.1124/dmd.113.053785. Epub 2013 Oct 4. Drug Metab Dispos. 2013. PMID: 24097902 Clinical Trial.

10

The mechanism of aphidicolin bioinactivation by rat liver in vitro systems.

Edelson RE, Gorycki PD, MacDonald TL. Edelson RE, et al. Among authors: gorycki pd. Xenobiotica. 1990 Mar;20(3):273-87. doi: 10.3109/00498259009046847. Xenobiotica. 1990. PMID: 2110702

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