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1997 3
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33 results

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Page 1
Syntaxin-5's flexibility in SNARE pairing supports Golgi functions.
D'Souza Z, Pokrovskaya I, Lupashin VV. D'Souza Z, et al. Traffic. 2023 Aug;24(8):355-379. doi: 10.1111/tra.12903. Epub 2023 Jun 21. Traffic. 2023. PMID: 37340984 Free PMC article.
Although two major Golgi v-SNAREs, GS28/GOSR1, and GS15/BET1L, are depleted in COG-deficient cells, the complete knockout of GS28 and GS15 only modestly affects Golgi glycosylation, indicating the existence of an adaptation mechanism in Golgi SNARE. ...
Although two major Golgi v-SNAREs, GS28/GOSR1, and GS15/BET1L, are depleted in COG-deficient cells, the complete knockout of GS28 and …
Gene expression in stress urinary incontinence: a systematic review.
Isali I, Mahran A, Khalifa AO, Sheyn D, Neudecker M, Qureshi A, Conroy B, Schumacher FR, Hijaz AK, El-Nashar SA. Isali I, et al. Int Urogynecol J. 2020 Jan;31(1):1-14. doi: 10.1007/s00192-019-04025-5. Epub 2019 Jul 16. Int Urogynecol J. 2020. PMID: 31312847
Eleven genes were overexpressed: skin-derived antileukoproteinase (SKALP/elafin), collagen type XVII alpha 1 chain (COL17A1), plakophilin 1 (PKP1), keratin 16 (KRT16), decorin (DCN), biglycan (BGN), protein bicaudal D homolog 2 (BICD2), growth factor receptor-bound protein 2 (GRB …
Eleven genes were overexpressed: skin-derived antileukoproteinase (SKALP/elafin), collagen type XVII alpha 1 chain (COL17A1), plakophilin 1 …
Structure and Expression Analyses of SVA Elements in Relation to Functional Genes.
Kwon YJ, Choi Y, Eo J, Noh YN, Gim JA, Jung YD, Lee JR, Kim HS. Kwon YJ, et al. Genomics Inform. 2013 Sep;11(3):142-8. doi: 10.5808/GI.2013.11.3.142. Epub 2013 Sep 30. Genomics Inform. 2013. PMID: 24124410 Free PMC article.
In an analysis of genomic structure, SVA elements are detected in the 5' untranslated region (UTR) of HGSNAT (SVA-B), MRGPRX3 (SVA-D), HYAL1 (SVA-F), TCHH (SVA-F), and ATXN2L (SVA-F) genes, while some elements are observed in the 3'UTR of SPICE1 (SVA-B), TDRKH (SVA-C), GOSR1 …
In an analysis of genomic structure, SVA elements are detected in the 5' untranslated region (UTR) of HGSNAT (SVA-B), MRGPRX3 (SVA-D), HYAL1 …
Characterisation of GLUT4 trafficking in HeLa cells: comparable kinetics and orthologous trafficking mechanisms to 3T3-L1 adipocytes.
Morris S, Geoghegan ND, Sadler JBA, Koester AM, Black HL, Laub M, Miller L, Heffernan L, Simpson JC, Mastick CC, Cooper J, Gadegaard N, Bryant NJ, Gould GW. Morris S, et al. PeerJ. 2020 Mar 5;8:e8751. doi: 10.7717/peerj.8751. eCollection 2020. PeerJ. 2020. PMID: 32185116 Free PMC article.
Here, we exemplify their utility through a small-scale siRNA screen to identify GOSR1 and YKT6 as potential novel regulators of GLUT4 trafficking in human cells....
Here, we exemplify their utility through a small-scale siRNA screen to identify GOSR1 and YKT6 as potential novel regulators of GLUT4 …
Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor.
Kerins MJ, Liu P, Tian W, Mannheim W, Zhang DD, Ooi A. Kerins MJ, et al. Mol Cell Biol. 2019 Jun 13;39(13):e00037-19. doi: 10.1128/MCB.00037-19. Print 2019 Jul 1. Mol Cell Biol. 2019. PMID: 31010806 Free PMC article.
Molecular validation of a subset of the enriched genes identified 8 high-confidence genes that negatively regulate NRF2 activity irrespective of cell type: ATG12, ATG7, GOSR1, IFT172, NRXN2, RAB6A, VPS37A, and the well-known negative regulator of NRF2, KEAP1 Of these, ATG1 …
Molecular validation of a subset of the enriched genes identified 8 high-confidence genes that negatively regulate NRF2 activity irrespectiv …
Identification of a novel SEREX antigen family, ECSA, in esophageal squamous cell carcinoma.
Kagaya A, Shimada H, Shiratori T, Kuboshima M, Nakashima-Fujita K, Yasuraoka M, Nishimori T, Kurei S, Hachiya T, Murakami A, Tamura Y, Nomura F, Ochiai T, Matsubara H, Takiguchi M, Hiwasa T. Kagaya A, et al. Proteome Sci. 2011 Jun 23;9(1):31. doi: 10.1186/1477-5956-9-31. Proteome Sci. 2011. PMID: 21696638 Free PMC article.
This peptide sequence was also conserved in FAM119A, GOSR1 and BBS5, suggesting that these are also ECSA family members. Reverse transcription followed by quantitative PCR analysis showed that the mRNA expression levels of ECSA-1, -2 and -3 and FAM119A but not of HCA25a, …
This peptide sequence was also conserved in FAM119A, GOSR1 and BBS5, suggesting that these are also ECSA family members. Reverse tran …
RNA Sequencing of Primary Cutaneous and Breast-Implant Associated Anaplastic Large Cell Lymphomas Reveals Infrequent Fusion Transcripts and Upregulation of PI3K/AKT Signaling via Neurotrophin Pathway Genes.
Di Napoli A, Vacca D, Bertolazzi G, Lopez G, Piane M, Germani A, Rogges E, Pepe G, Santanelli Di Pompeo F, Salgarello M, Jobanputra V, Hsiao S, Wrzeszczynski KO, Berti E, Bhagat G. Di Napoli A, et al. Cancers (Basel). 2021 Dec 7;13(24):6174. doi: 10.3390/cancers13246174. Cancers (Basel). 2021. PMID: 34944796 Free PMC article.
By performing RNA sequencing of 1385 genes (TruSight RNA Pan-Cancer, Illumina) in 12 cALCLs, 10 BI-ALCLs and two anaplastic lymphoma kinase (ALK)-positive sALCLs, we identified the previously reported TYK2-NPM1 fusion in 1 cALCL (1/12, 8%), and four new intrachromosomal gene fusi …
By performing RNA sequencing of 1385 genes (TruSight RNA Pan-Cancer, Illumina) in 12 cALCLs, 10 BI-ALCLs and two anaplastic lymphoma kinase …
GARP dysfunction results in COPI displacement, depletion of Golgi v-SNAREs and calcium homeostasis proteins.
Khakurel A, Kudlyk T, Pokrovskaya I, D'Souza Z, Lupashin VV. Khakurel A, et al. Front Cell Dev Biol. 2022 Dec 12;10:1066504. doi: 10.3389/fcell.2022.1066504. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36578782 Free PMC article.
Validation of proteomics studies revealed that SDF4 and ATP2C1, related to Golgi calcium homeostasis, as well as intra-Golgi v-SNAREs GOSR1 and BET1L, were significantly depleted in GARP-KO cells. Finding that GARP-KO is more deleterious to Golgi physiology than deletion o …
Validation of proteomics studies revealed that SDF4 and ATP2C1, related to Golgi calcium homeostasis, as well as intra-Golgi v-SNAREs GOS …
cDNA characterization and chromosomal mapping of human golgi SNARE GS27 and GS28 to chromosome 17.
Bui TD, Levy ER, Subramaniam VN, Lowe SL, Hong W. Bui TD, et al. Genomics. 1999 Apr 15;57(2):285-8. doi: 10.1006/geno.1998.5649. Genomics. 1999. PMID: 10198168
Two proteins, Golgi SNAREs of 27 kDa, GS27, and of 28 kDa, GS28 (HGMW-approved nomenclature GOSR2 and GOSR1, respectively), are important trafficking membrane proteins between the endoplasmic reticulum and the Golgi and between Golgi subcompartments. ...
Two proteins, Golgi SNAREs of 27 kDa, GS27, and of 28 kDa, GS28 (HGMW-approved nomenclature GOSR2 and GOSR1, respectively), are impor …
Identification of multiple complex rearrangements associated with deletions in the 6q23-27 region in Sézary syndrome.
Iżykowska K, Zawada M, Nowicka K, Grabarczyk P, Braun FCM, Delin M, Möbs M, Beyer M, Sterry W, Schmidt CA, Przybylski GK. Iżykowska K, et al. J Invest Dermatol. 2013 Nov;133(11):2617-2625. doi: 10.1038/jid.2013.188. Epub 2013 Apr 18. J Invest Dermatol. 2013. PMID: 23698072 Free article.
Five gene fusions were identified, of which two, CCDC28A-IL22RA2 and AIG1-GOSR1, both in SeAx, were in the same orientation and were expressed at the messenger RNA level....
Five gene fusions were identified, of which two, CCDC28A-IL22RA2 and AIG1-GOSR1, both in SeAx, were in the same orientation and were …
33 results