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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1979 1
1982 1
1990 1
2004 1
2006 1
2009 1
2011 1
2013 2
2016 1
2017 1
2018 1
2021 0
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11 results
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Page 1
A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine.
DeWire SM, Yamashita DS, Rominger DH, Liu G, Cowan CL, Graczyk TM, Chen XT, Pitis PM, Gotchev D, Yuan C, Koblish M, Lark MW, Violin JD. DeWire SM, et al. Among authors: gotchev d. J Pharmacol Exp Ther. 2013 Mar;344(3):708-17. doi: 10.1124/jpet.112.201616. Epub 2013 Jan 8. J Pharmacol Exp Ther. 2013. PMID: 23300227
Structure-activity relationships and discovery of a G protein biased μ opioid receptor ligand, [(3-methoxythiophen-2-yl)methyl]({2-[(9R)-9-(pyridin-2-yl)-6-oxaspiro-[4.5]decan-9-yl]ethyl})amine (TRV130), for the treatment of acute severe pain.
Chen XT, Pitis P, Liu G, Yuan C, Gotchev D, Cowan CL, Rominger DH, Koblish M, Dewire SM, Crombie AL, Violin JD, Yamashita DS. Chen XT, et al. Among authors: gotchev d. J Med Chem. 2013 Oct 24;56(20):8019-31. doi: 10.1021/jm4010829. Epub 2013 Oct 14. J Med Chem. 2013. PMID: 24063433
HBsAg mRNA degradation induced by a dihydroquinolizinone compound depends on the HBV posttranscriptional regulatory element.
Zhou T, Block T, Liu F, Kondratowicz AS, Sun L, Rawat S, Branson J, Guo F, Steuer HM, Liang H, Bailey L, Moore C, Wang X, Cuconatti A, Gao M, Lee ACH, Harasym T, Chiu T, Gotchev D, Dorsey B, Rijnbrand R, Sofia MJ. Zhou T, et al. Among authors: gotchev d. Antiviral Res. 2018 Jan;149:191-201. doi: 10.1016/j.antiviral.2017.11.009. Epub 2017 Nov 10. Antiviral Res. 2018. PMID: 29133129
Spongipyran Synthetic Studies. Evolution of a Scalable Total Synthesis of (+)-Spongistatin 1.
Smith AB, Sfouggatakis C, Risatti CA, Sperry JB, Zhu W, Doughty VA, Tomioka T, Gotchev DB, Bennett CS, Sakamoto S, Atasoylu O, Shirakami S, Bauer D, Takeuchi M, Koyanagi J, Sakamoto Y. Smith AB, et al. Among authors: gotchev db. Tetrahedron. 2009 Sep 15;65(33):6489-6509. doi: 10.1016/j.tet.2009.04.003. Tetrahedron. 2009. PMID: 20640040 Free PMC article.
Polymeric pyelotomy (experimental studies).
Gotchev D, Moneva-Antonova L, Mladenov I. Gotchev D, et al. Int Urol Nephrol. 1979;11(4):279-88. doi: 10.1007/BF02086814. Int Urol Nephrol. 1979. PMID: 536176
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