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PKR modulates abnormal brain signaling in experimental obesity.

Taga M, Mouton-Liger F, Sadoune M, Gourmaud S, Norman J, Tible M, Thomasseau S, Paquet C, Nicoll JAR, Boche D, Hugon J. Taga M, et al. Among authors: gourmaud s. PLoS One. 2018 May 24;13(5):e0196983. doi: 10.1371/journal.pone.0196983. eCollection 2018. PLoS One. 2018. PMID: 29795582 Free PMC article.

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The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease.

Gourmaud S, Stewart DA, Irwin DJ, Roberts N, Barbour AJ, Eberwine G, O'Brien WT, Vassar R, Talos DM, Jensen FE. Gourmaud S, et al. Brain. 2022 Mar 29;145(1):324-339. doi: 10.1093/brain/awab268. Brain. 2022. PMID: 34264340 Free PMC article.

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Alzheimer-like amyloid and tau alterations associated with cognitive deficit in temporal lobe epilepsy.

Gourmaud S, Shou H, Irwin DJ, Sansalone K, Jacobs LM, Lucas TH, Marsh ED, Davis KA, Jensen FE, Talos DM. Gourmaud S, et al. Brain. 2020 Jan 1;143(1):191-209. doi: 10.1093/brain/awz381. Brain. 2020. PMID: 31834353 Free PMC article.

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PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.

Tible M, Mouton Liger F, Schmitt J, Giralt A, Farid K, Thomasseau S, Gourmaud S, Paquet C, Rondi Reig L, Meurs E, Girault JA, Hugon J. Tible M, et al. Among authors: gourmaud s. Aging Cell. 2019 Jun;18(3):e12887. doi: 10.1111/acel.12887. Epub 2019 Mar 1. Aging Cell. 2019. PMID: 30821420 Free PMC article.

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Brimapitide Reduced Neuronal Stress Markers and Cognitive Deficits in 5XFAD Transgenic Mice.

Gourmaud S, Thomas P, Thomasseau S, Tible M, Abadie C, Paquet C, Hugon J. Gourmaud S, et al. J Alzheimers Dis. 2018;63(2):665-674. doi: 10.3233/JAD-171099. J Alzheimers Dis. 2018. PMID: 29660941

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Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy.

Talos DM, Jacobs LM, Gourmaud S, Coto CA, Sun H, Lim KC, Lucas TH, Davis KA, Martinez-Lage M, Jensen FE. Talos DM, et al. Among authors: gourmaud s. Ann Neurol. 2018 Feb;83(2):311-327. doi: 10.1002/ana.25149. Epub 2018 Feb 15. Ann Neurol. 2018. PMID: 29331082 Free PMC article.

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Effect of anti-cancer drugs on microglia in patient-derived breast cancer xenografted mouse models.

Paquet C, Boche D, El Bouchtaoui M, Gourmaud S, Janin A, Bousquet G. Paquet C, et al. Among authors: gourmaud s. Neuropathology. 2017 Feb;37(1):91-93. doi: 10.1111/neup.12323. Epub 2016 Jul 20. Neuropathology. 2017. PMID: 27436167 No abstract available.

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Dual Kinase Inhibition Affords Extended in vitro Neuroprotection in Amyloid-β Toxicity.

Gourmaud S, Mouton-Liger F, Abadie C, Meurs EF, Paquet C, Hugon J. Gourmaud S, et al. J Alzheimers Dis. 2016 Oct 18;54(4):1659-1670. doi: 10.3233/JAD-160509. J Alzheimers Dis. 2016. PMID: 27636848

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Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease.

Poesen K, De Schaepdryver M, Stubendorff B, Gille B, Muckova P, Wendler S, Prell T, Ringer TM, Rhode H, Stevens O, Claeys KG, Couwelier G, D'Hondt A, Lamaire N, Tilkin P, Van Reijen D, Gourmaud S, Fedtke N, Heiling B, Rumpel M, Rödiger A, Gunkel A, Witte OW, Paquet C, Vandenberghe R, Grosskreutz J, Van Damme P. Poesen K, et al. Among authors: gourmaud s. Neurology. 2017 Jun 13;88(24):2302-2309. doi: 10.1212/WNL.0000000000004029. Epub 2017 May 12. Neurology. 2017. PMID: 28500227

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PKR downregulation prevents neurodegeneration and β-amyloid production in a thiamine-deficient model.

Mouton-Liger F, Rebillat AS, Gourmaud S, Paquet C, Leguen A, Dumurgier J, Bernadelli P, Taupin V, Pradier L, Rooney T, Hugon J. Mouton-Liger F, et al. Among authors: gourmaud s. Cell Death Dis. 2015 Jan 15;6(1):e1594. doi: 10.1038/cddis.2014.552. Cell Death Dis. 2015. PMID: 25590804 Free PMC article.

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