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Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation.
Fong JY, Pignata L, Goy PA, Kawabata KC, Lee SC, Koh CM, Musiani D, Massignani E, Kotini AG, Penson A, Wun CM, Shen Y, Schwarz M, Low DH, Rialdi A, Ki M, Wollmann H, Mzoughi S, Gay F, Thompson C, Hart T, Barbash O, Luciani GM, Szewczyk MM, Wouters BJ, Delwel R, Papapetrou EP, Barsyte-Lovejoy D, Arrowsmith CH, Minden MD, Jin J, Melnick A, Bonaldi T, Abdel-Wahab O, Guccione E. Fong JY, et al. Among authors: goy pa. Cancer Cell. 2019 Aug 12;36(2):194-209.e9. doi: 10.1016/j.ccell.2019.07.003. Cancer Cell. 2019. PMID: 31408619 Free PMC article.
Identification of Quinolinols as Activators of TEAD-Dependent Transcription.
Pobbati AV, Mejuch T, Chakraborty S, Karatas H, Bharath SR, Guéret SM, Goy PA, Hahne G, Pahl A, Sievers S, Guccione E, Song H, Waldmann H, Hong W. Pobbati AV, et al. Among authors: goy pa. ACS Chem Biol. 2019 Dec 20;14(12):2909-2921. doi: 10.1021/acschembio.9b00786. Epub 2019 Dec 2. ACS Chem Biol. 2019. PMID: 31742995 Free article.
An interplay between BRD4 and G9a regulates skeletal myogenesis.
Yang N, Das D, Shankar SR, Goy PA, Guccione E, Taneja R. Yang N, et al. Among authors: goy pa. Front Cell Dev Biol. 2022 Sep 7;10:978931. doi: 10.3389/fcell.2022.978931. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36158208 Free PMC article.
MBNL1 alternative splicing isoforms play opposing roles in cancer.
Tabaglio T, Low DH, Teo WKL, Goy PA, Cywoniuk P, Wollmann H, Ho J, Tan D, Aw J, Pavesi A, Sobczak K, Wee DKB, Guccione E. Tabaglio T, et al. Among authors: goy pa. Life Sci Alliance. 2018 Sep 7;1(5):e201800157. doi: 10.26508/lsa.201800157. eCollection 2018 Oct. Life Sci Alliance. 2018. PMID: 30456384 Free PMC article.
Mitchell-Riley syndrome iPSCs exhibit reduced pancreatic endoderm differentiation due to a mutation in RFX6.
Trott J, Alpagu Y, Tan EK, Shboul M, Dawood Y, Elsy M, Wollmann H, Tano V, Bonnard C, Eng S, Narayanan G, Junnarkar S, Wearne S, Strutt J, Kumar A, Tomaz LB, Goy PA, Mzoughi S, Jennings R, Hagoort J, Eskin A, Lee H, Nelson SF, Al-Kazaleh F, El-Khateeb M, Fathallah R, Shah H, Goeke J, Langley SR, Guccione E, Hanley N, De Bakker BS, Reversade B, Dunn NR. Trott J, et al. Among authors: goy pa. Development. 2020 Nov 5;147(21):dev194878. doi: 10.1242/dev.194878. Development. 2020. PMID: 33033118