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Protein complexes in cells by AI-assisted structural proteomics.
O'Reilly FJ, Graziadei A, Forbrig C, Bremenkamp R, Charles K, Lenz S, Elfmann C, Fischer L, Stülke J, Rappsilber J. O'Reilly FJ, et al. Among authors: graziadei a. Mol Syst Biol. 2023 Apr 12;19(4):e11544. doi: 10.15252/msb.202311544. Epub 2023 Feb 23. Mol Syst Biol. 2023. PMID: 36815589 Free PMC article.
Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Le-Trilling VTK, Banchenko S, Paydar D, Leipe PM, Binting L, Lauer S, Graziadei A, Klingen R, Gotthold C, Bürger J, Bracht T, Sitek B, Jan Lebbink R, Malyshkina A, Mielke T, Rappsilber J, Spahn CM, Voigt S, Trilling M, Schwefel D. Le-Trilling VTK, et al. Among authors: graziadei a. EMBO J. 2023 Mar 1;42(5):e112351. doi: 10.15252/embj.2022112351. Epub 2023 Feb 10. EMBO J. 2023. PMID: 36762436 Free PMC article.
Cryo-EM structure of the fully assembled Elongator complex.
Jaciuk M, Scherf D, Kaszuba K, Gaik M, Rau A, Kościelniak A, Krutyhołowa R, Rawski M, Indyka P, Graziadei A, Chramiec-Głąbik A, Biela A, Dobosz D, Lin TY, Abbassi NE, Hammermeister A, Rappsilber J, Kosinski J, Schaffrath R, Glatt S. Jaciuk M, et al. Among authors: graziadei a. Nucleic Acids Res. 2023 Mar 21;51(5):2011-2032. doi: 10.1093/nar/gkac1232. Nucleic Acids Res. 2023. PMID: 36617428 Free PMC article.
In-cell architecture of an actively transcribing-translating expressome.
O'Reilly FJ, Xue L, Graziadei A, Sinn L, Lenz S, Tegunov D, Blötz C, Singh N, Hagen WJH, Cramer P, Stülke J, Mahamid J, Rappsilber J. O'Reilly FJ, et al. Among authors: graziadei a. Science. 2020 Jul 31;369(6503):554-557. doi: 10.1126/science.abb3758. Science. 2020. PMID: 32732422 Free PMC article.
The sterol transporter STARD3 transports sphingosine at ER-lysosome contact sites.
Hempelmann P, Lolicato F, Graziadei A, Brown RDR, Spiegel S, Rappsilber J, Nickel W, Höglinger D, Jamecna D. Hempelmann P, et al. Among authors: graziadei a. bioRxiv [Preprint]. 2023 Sep 18:2023.09.18.557036. doi: 10.1101/2023.09.18.557036. bioRxiv. 2023. PMID: 37790546 Free PMC article. Preprint.
15 results