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Year Number of Results
2016 1
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2018 2
2019 4
2020 1
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2022 4
2023 1
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Page 1
In vivo prime editing of a metabolic liver disease in mice.
Böck D, Rothgangl T, Villiger L, Schmidheini L, Matsushita M, Mathis N, Ioannidi E, Rimann N, Grisch-Chan HM, Kreutzer S, Kontarakis Z, Kopf M, Thöny B, Schwank G. Böck D, et al. Among authors: grisch chan hm. Sci Transl Med. 2022 Mar 16;14(636):eabl9238. doi: 10.1126/scitranslmed.abl9238. Epub 2022 Mar 16. Sci Transl Med. 2022. PMID: 35294257 Free PMC article.
State-of-the-Art 2019 on Gene Therapy for Phenylketonuria.
Grisch-Chan HM, Schwank G, Harding CO, Thöny B. Grisch-Chan HM, et al. Hum Gene Ther. 2019 Oct;30(10):1274-1283. doi: 10.1089/hum.2019.111. Epub 2019 Sep 9. Hum Gene Ther. 2019. PMID: 31364419 Free PMC article. Review.
Comprehensive characterization of ureagenesis in the spfash mouse, a model of human ornithine transcarbamylase deficiency, reveals age-dependency of ammonia detoxification.
Allegri G, Deplazes S, Rimann N, Causton B, Scherer T, Leff JW, Diez-Fernandez C, Klimovskaia A, Fingerhut R, Krijt J, Kožich V, Nuoffer JM, Grisch-Chan HM, Thöny B, Häberle J. Allegri G, et al. Among authors: grisch chan hm. J Inherit Metab Dis. 2019 Nov;42(6):1064-1076. doi: 10.1002/jimd.12068. Epub 2019 Mar 13. J Inherit Metab Dis. 2019. PMID: 30714172 Review.
Core-Shell Structured Chitosan-Polyethylenimine Nanoparticles for Gene Delivery: Improved Stability, Cellular Uptake, and Transfection Efficiency.
Casper J, Nicolle L, Willimann M, Kuzucu EÜ, Tran A, Robin P, Detampel P, Grisch-Chan HM, Thöny B, Huwyler J, Gerber-Lemaire S. Casper J, et al. Among authors: grisch chan hm. Macromol Biosci. 2023 Jan;23(1):e2200314. doi: 10.1002/mabi.202200314. Epub 2022 Oct 18. Macromol Biosci. 2023. PMID: 36200651 Free article.
Intrabiliary infusion of naked DNA vectors targets periportal hepatocytes in mice.
Deplazes S, Schlegel A, Song Z, Allegri G, Rimann N, Scherer T, Willimann M, Opitz L, Cunningham SC, Alexander IE, Kipar A, Häberle J, Thöny B, Grisch-Chan HM. Deplazes S, et al. Among authors: grisch chan hm. Mol Ther Methods Clin Dev. 2022 Oct 10;27:352-367. doi: 10.1016/j.omtm.2022.10.006. eCollection 2022 Dec 8. Mol Ther Methods Clin Dev. 2022. PMID: 36381301 Free PMC article.
Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids.
Buck J, Mueller D, Mettal U, Ackermann M, Grisch-Chan HM, Thöny B, Zumbuehl A, Huwyler J, Witzigmann D. Buck J, et al. Among authors: grisch chan hm. ACS Omega. 2020 Sep 15;5(38):24724-24732. doi: 10.1021/acsomega.0c03303. eCollection 2020 Sep 29. ACS Omega. 2020. PMID: 33015490 Free PMC article.
Treatment of a metabolic liver disease by in vivo genome base editing in adult mice.
Villiger L, Grisch-Chan HM, Lindsay H, Ringnalda F, Pogliano CB, Allegri G, Fingerhut R, Häberle J, Matos J, Robinson MD, Thöny B, Schwank G. Villiger L, et al. Among authors: grisch chan hm. Nat Med. 2018 Oct;24(10):1519-1525. doi: 10.1038/s41591-018-0209-1. Epub 2018 Oct 8. Nat Med. 2018. PMID: 30297904 Free article.
15 results