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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1997 1
1999 2
2000 5
2001 5
2002 4
2003 4
2005 2
2006 1
2007 2
2008 5
2009 3
2010 2
2011 3
2012 4
2014 1
2015 1
2016 1
2017 1
2019 1
2020 2
2021 3
2024 0

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46 results

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Page 1
Novel (R)-6,6a,7,8,9,10-hexahydro-5H-pyrazino[1,2-a][1,n]naphthyridines as potent and selective agonists of the 5-HT2C receptor.
Schrader TO, Zhu X, Kasem M, Ren A, Liu C, Wu C, Dang H, Le M, Gatlin J, Chase K, Frazer J, Whelan KT, Grottick AJ, Hutton C, Barden J, Chen C, Ortiz A, Feichtinger K, Semple G. Schrader TO, et al. Among authors: grottick aj. Bioorg Med Chem Lett. 2021 Apr 15;38:127872. doi: 10.1016/j.bmcl.2021.127872. Epub 2021 Feb 23. Bioorg Med Chem Lett. 2021. PMID: 33636307
Diet-induced models of obesity (DIO) in rodents.
Bagnol D, Al-Shamma HA, Behan D, Whelan K, Grottick AJ. Bagnol D, et al. Among authors: grottick aj. Curr Protoc Neurosci. 2012 Apr;Chapter 9:Unit 9.38.1-13. doi: 10.1002/0471142301.ns0938s59. Curr Protoc Neurosci. 2012. PMID: 22470151
Discovery of a lead series of potent benzodiazepine 5-HT2C receptor agonists with high selectivity in functional and binding assays.
Ren A, Zhu X, Feichtinger K, Lehman J, Kasem M, Schrader TO, Wong A, Dang H, Le M, Frazer J, Unett DJ, Grottick AJ, Whelan KT, Morgan ME, Sage CR, Semple G. Ren A, et al. Among authors: grottick aj. Bioorg Med Chem Lett. 2020 Mar 1;30(5):126929. doi: 10.1016/j.bmcl.2019.126929. Epub 2019 Dec 26. Bioorg Med Chem Lett. 2020. PMID: 31952960
Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain.
Han S, Thoresen L, Jung JK, Zhu X, Thatte J, Solomon M, Gaidarov I, Unett DJ, Yoon WH, Barden J, Sadeque A, Usmani A, Chen C, Semple G, Grottick AJ, Al-Shamma H, Christopher R, Jones RM. Han S, et al. Among authors: grottick aj. ACS Med Chem Lett. 2017 Nov 30;8(12):1309-1313. doi: 10.1021/acsmedchemlett.7b00396. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259753 Free PMC article.
Pyrimidine-based antagonists of h-MCH-R1 derived from ATC0175: in vitro profiling and in vivo evaluation.
Semple G, Tran TA, Kramer B, Hsu D, Han S, Choi J, Vallar P, Casper MD, Zou N, Hauser EK, Thomsen W, Whelan K, Sengupta D, Morgan M, Sekiguchi Y, Kanuma K, Chaki S, Grottick AJ. Semple G, et al. Among authors: grottick aj. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6166-71. doi: 10.1016/j.bmcl.2009.09.003. Epub 2009 Sep 6. Bioorg Med Chem Lett. 2009. PMID: 19773162
46 results