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An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.
Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, Lee JM, Cirrito JR. Sheline YI, et al. Among authors: grzelak mv. Sci Transl Med. 2014 May 14;6(236):236re4. doi: 10.1126/scitranslmed.3008169. Sci Transl Med. 2014. PMID: 24828079 Free PMC article. Clinical Trial.