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Year Number of Results
1962 1
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1988 1
1996 2
1997 1
1998 1
1999 2
2000 3
2002 1
2004 2
2005 5
2006 5
2007 6
2008 3
2009 6
2010 2
2011 4
2012 4
2013 8
2014 10
2015 15
2016 11
2017 15
2018 7
2019 9
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2025 3

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144 results

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Page 1
Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates.
Brown KM, Nair JK, Janas MM, Anglero-Rodriguez YI, Dang LTH, Peng H, Theile CS, Castellanos-Rizaldos E, Brown C, Foster D, Kurz J, Allen J, Maganti R, Li J, Matsuda S, Stricos M, Chickering T, Jung M, Wassarman K, Rollins J, Woods L, Kelin A, Guenther DC, Mobley MW, Petrulis J, McDougall R, Racie T, Bombardier J, Cha D, Agarwal S, Johnson L, Jiang Y, Lentini S, Gilbert J, Nguyen T, Chigas S, LeBlanc S, Poreci U, Kasper A, Rogers AB, Chong S, Davis W, Sutherland JE, Castoreno A, Milstein S, Schlegel MK, Zlatev I, Charisse K, Keating M, Manoharan M, Fitzgerald K, Wu JT, Maier MA, Jadhav V. Brown KM, et al. Among authors: guenther dc. Nat Biotechnol. 2022 Oct;40(10):1500-1508. doi: 10.1038/s41587-022-01334-x. Epub 2022 Jun 2. Nat Biotechnol. 2022. PMID: 35654979
The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine-Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human.
McDougall R, Ramsden D, Agarwal S, Agarwal S, Aluri K, Arciprete M, Brown C, Castellanos-Rizaldos E, Charisse K, Chong S, Cichocki J, Fitzgerald K, Goel V, Gu Y, Guenther D, Habtemariam B, Jadhav V, Janas M, Jayaraman M, Kurz J, Li J, Liu J, Liu X, Liou S, Maclauchlin C, Maier M, Manoharan M, Nair JK, Robbie G, Schmidt K, Smith P, Theile C, Vaishnaw A, Waldron S, Xu Y, Zhang X, Zlatev I, Wu JT. McDougall R, et al. Among authors: guenther d. Drug Metab Dispos. 2022 Jun;50(6):781-797. doi: 10.1124/dmd.121.000428. Epub 2021 Jun 21. Drug Metab Dispos. 2022. PMID: 34154993 Free article. Review.
Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates.
Yu M, Qin J, Liu X, Ramsden D, Williams B, Zlatev I, Guenther D, Matsuda S, Tymon R, Darcy J, Wong C, Tsung J, Zawaneh P, Chong S, Theile CS, Taneja N, Rogers A, Liu J, Castellanos-Rizaldos E, Bond S, So K, Denoncourt J, Castoreno A, Manoharan M, Wu JT, Fitzgerald K, Maier MA, Jadhav V, Nair JK. Yu M, et al. Among authors: guenther d. Nucleic Acids Res. 2024 Jun 10;52(10):5423-5437. doi: 10.1093/nar/gkae350. Nucleic Acids Res. 2024. PMID: 38742636 Free PMC article.
Late-stage rehabilitation after anterior cruciate ligament reconstruction: A multicentre randomised controlled trial (PReP).
Niederer D, Keller M, Schüttler KF, Schoepp C, Petersen W, Best R, Mengis N, Mehl J, Krause M, Jakob S, Wießmeier M, Vogt L, Pinggera L, Guenther D, Ellermann A, Efe T, Groneberg DA, Behringer M, Stein T. Niederer D, et al. Among authors: guenther d. Ann Phys Rehabil Med. 2024 May;67(4):101827. doi: 10.1016/j.rehab.2024.101827. Epub 2024 Mar 12. Ann Phys Rehabil Med. 2024. PMID: 38479249 Free article. Clinical Trial.
Anterolateral ligament of the knee, fact or fiction?
Musahl V, Rahnemai-Azar AA, van Eck CF, Guenther D, Fu FH. Musahl V, et al. Among authors: guenther d. Knee Surg Sports Traumatol Arthrosc. 2016 Jan;24(1):2-3. doi: 10.1007/s00167-015-3913-0. Knee Surg Sports Traumatol Arthrosc. 2016. PMID: 26694486 No abstract available.
Beyond the Anterolateral Ligament: Response.
Guenther D, Fu FH, Musahl V, Debski RE. Guenther D, et al. Am J Sports Med. 2017 May;45(6):NP18-NP19. doi: 10.1177/0363546517698924. Am J Sports Med. 2017. PMID: 28459644 No abstract available.
Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
Matsuda S, Bala S, Liao JY, Datta D, Mikami A, Woods L, Harp JM, Gilbert JA, Bisbe A, Manoharan RM, Kim M, Theile CS, Guenther DC, Jiang Y, Agarwal S, Maganti R, Schlegel MK, Zlatev I, Charisse K, Rajeev KG, Castoreno A, Maier M, Janas MM, Egli M, Chaput JC, Manoharan M. Matsuda S, et al. Among authors: guenther dc. J Am Chem Soc. 2023 Sep 13;145(36):19691-19706. doi: 10.1021/jacs.3c04744. Epub 2023 Aug 28. J Am Chem Soc. 2023. PMID: 37638886 Free article.
Anterolateral rotatory instability of the knee.
Guenther D, Griffith C, Lesniak B, Lopomo N, Grassi A, Zaffagnini S, Fu FH, Musahl V. Guenther D, et al. Knee Surg Sports Traumatol Arthrosc. 2015 Oct;23(10):2909-17. doi: 10.1007/s00167-015-3616-6. Epub 2015 May 5. Knee Surg Sports Traumatol Arthrosc. 2015. PMID: 25941044 Review.
144 results