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Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity.

Ipe J, Li R, Metzger IF, Bo Li Lu J, Gufford BT, Desta Z, Liu Y, Skaar TC. Ipe J, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2021 Feb;109(2):485-493. doi: 10.1002/cpt.2018. Epub 2020 Oct 5. Clin Pharmacol Ther. 2021. PMID: 32772362 Free PMC article.

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Implementation of a pharmacogenomics consult service to support the INGENIOUS trial.

Eadon MT, Desta Z, Levy KD, Decker BS, Pierson RC, Pratt VM, Callaghan JT, Rosenman MB, Carpenter JS, Holmes AM, McDonald CA, Benson EA, Patil AS, Vuppalanchi R, Gufford BT, Dave N, Robarge JD, Hyder MA, Haas DM, Kreutz RP, Dexter PR, Skaar TC, Flockhart DA. Eadon MT, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2016 Jul;100(1):63-6. doi: 10.1002/cpt.347. Epub 2016 Mar 31. Clin Pharmacol Ther. 2016. PMID: 26850569 Free PMC article. Review.

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Pharmacogenetics and Practice: Tailoring Prescribing for Safety and Effectiveness.

Fulton CR, Swart M, De Luca T, Liu SN, Collins KS, Desta Z, Gufford BT, Eadon MT. Fulton CR, et al. Among authors: gufford bt. J Nurse Pract. 2018 Nov-Dec;14(10):697-704.e1. doi: 10.1016/j.nurpra.2018.09.021. Epub 2018 Nov 2. J Nurse Pract. 2018. PMID: 30555285 Free PMC article. No abstract available.

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Mass balance and pharmacokinetics of an oral dose of ¹⁴ C-napabucasin in healthy adult male subjects.

Dai X, Karol MD, Hitron M, Hard ML, Blanchard JE, Eraut NCJE, Rich N, Gufford BT. Dai X, et al. Among authors: gufford bt. Pharmacol Res Perspect. 2021 Feb;9(1):e00722. doi: 10.1002/prp2.722. Pharmacol Res Perspect. 2021. PMID: 33576192 Free PMC article. Clinical Trial.

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Probenecid-Boosted Tenofovir: A Physiologically-Based Pharmacokinetic Model-Informed Strategy for On-Demand HIV Preexposure Prophylaxis.

Liu SN, Desta Z, Gufford BT. Liu SN, et al. Among authors: gufford bt. CPT Pharmacometrics Syst Pharmacol. 2020 Jan;9(1):40-47. doi: 10.1002/psp4.12481. Epub 2019 Dec 23. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 31749296 Free PMC article.

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Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On-Demand HIV Preexposure Prophylaxis.

Liu SN, Gufford BT, Lu JBL, Bushman LR, Anderson PL, Bergstrom RF, Desta Z, Gupta SK. Liu SN, et al. Among authors: gufford bt. Clin Pharmacol Ther. 2020 May;107(5):1200-1208. doi: 10.1002/cpt.1714. Epub 2019 Dec 31. Clin Pharmacol Ther. 2020. PMID: 31675437 Free PMC article. Clinical Trial.

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A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies.

Birer-Williams C, Gufford BT, Chou E, Alilio M, VanAlstine S, Morley RE, McCune JS, Paine MF, Boyce RD. Birer-Williams C, et al. Among authors: gufford bt. Drug Metab Dispos. 2020 Oct;48(10):1104-1112. doi: 10.1124/dmd.120.000054. Epub 2020 Jun 29. Drug Metab Dispos. 2020. PMID: 32601103 Free PMC article.

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Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo.

Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z. Gufford BT, et al. Drug Metab Dispos. 2016 Apr;44(4):544-53. doi: 10.1124/dmd.115.068908. Epub 2016 Jan 22. Drug Metab Dispos. 2016. PMID: 26802129 Free PMC article. Clinical Trial.

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Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial.

Fulton CR, Zang Y, Desta Z, Rosenman MB, Holmes AM, Decker BS, Zhang Y, T Callaghan J, Pratt VM, Levy KD, Gufford BT, Dexter PR, Skaar TC, Eadon MT. Fulton CR, et al. Among authors: gufford bt. Pharmacogenomics. 2019 Apr;20(6):397-408. doi: 10.2217/pgs-2018-0205. Epub 2019 Feb 20. Pharmacogenomics. 2019. PMID: 30784356 Free PMC article. Clinical Trial.

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Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.

Liu SN, Lu JBL, Watson CJW, Lazarus P, Desta Z, Gufford BT. Liu SN, et al. Among authors: gufford bt. Drug Metab Dispos. 2019 May;47(5):535-544. doi: 10.1124/dmd.118.085035. Epub 2019 Feb 25. Drug Metab Dispos. 2019. PMID: 30804050 Free PMC article.

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