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Probiotic-guided CAR-T cells for solid tumor targeting.
Vincent RL, Gurbatri CR, Li F, Vardoshvili A, Coker C, Im J, Ballister ER, Rouanne M, Savage T, de Los Santos-Alexis K, Redenti A, Brockmann L, Komaranchath M, Arpaia N, Danino T. Vincent RL, et al. Among authors: gurbatri cr. Science. 2023 Oct 13;382(6667):211-218. doi: 10.1126/science.add7034. Epub 2023 Oct 12. Science. 2023. PMID: 37824640
Engineering bacteria as interactive cancer therapies.
Gurbatri CR, Arpaia N, Danino T. Gurbatri CR, et al. Science. 2022 Nov 25;378(6622):858-864. doi: 10.1126/science.add9667. Epub 2022 Nov 24. Science. 2022. PMID: 36423303 Free PMC article. Review.
Colorectal cancer detection and treatment with engineered probiotics.
Gurbatri CR, Radford G, Vrbanac L, Coker C, Im JW, Taylor SR, Jang Y, Sivan A, Rhee K, Saleh AA, Chien T, Zandkarimi F, Lia I, Lannagan TR, Wang T, Wright JA, Thomas E, Kobayashi H, Ng JQ, Lawrence M, Sammour T, Thomas M, Lewis M, Papanicolas L, Perry J, Fitzsimmons T, Kaazan P, Lim A, Marker J, Ostroff C, Rogers G, Arpaia N, Worthley DL, Woods SL, Danino T. Gurbatri CR, et al. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535370. doi: 10.1101/2023.04.03.535370. bioRxiv. 2023. PMID: 37066243 Free PMC article. Preprint.
Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.
Gurbatri CR, Radford GA, Vrbanac L, Im J, Thomas EM, Coker C, Taylor SR, Jang Y, Sivan A, Rhee K, Saleh AA, Chien T, Zandkarimi F, Lia I, Lannagan TRM, Wang T, Wright JA, Kobayashi H, Ng JQ, Lawrence M, Sammour T, Thomas M, Lewis M, Papanicolas L, Perry J, Fitzsimmons T, Kaazan P, Lim A, Stavropoulos AM, Gouskos DA, Marker J, Ostroff C, Rogers G, Arpaia N, Worthley DL, Woods SL, Danino T. Gurbatri CR, et al. Nat Commun. 2024 Jan 20;15(1):646. doi: 10.1038/s41467-024-44776-4. Nat Commun. 2024. PMID: 38245513 Free PMC article. Clinical Trial.