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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 7
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58 results

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2 articles found by citation matching

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Page 1
Towards a unified mechanistic theory of aging.
Barja G. Barja G. Exp Gerontol. 2019 Sep;124:110627. doi: 10.1016/j.exger.2019.05.016. Epub 2019 Jun 5. Exp Gerontol. 2019. PMID: 31173843 Review.
Aging effectors include mitROS production, lipid unsaturation, autophagy, mitochondrial DNA repair and possibly others like apoptosis, proteostasis, or telomere shortening, corresponding to different classic theories of aging. ...The aging regulating system r
Aging effectors include mitROS production, lipid unsaturation, autophagy, mitochondrial DNA repair and possibly others like apoptosis
Free radicals and aging.
Barja G. Barja G. Trends Neurosci. 2004 Oct;27(10):595-600. doi: 10.1016/j.tins.2004.07.005. Trends Neurosci. 2004. PMID: 15374670 Review.
Oxygen radicals are increasingly considered responsible for part of these aging changes. Comparative studies of animals with different aging rates have shown that the rate of mitochondrial oxygen radical generation is directly related to the steady-state level of ox …
Oxygen radicals are increasingly considered responsible for part of these aging changes. Comparative studies of animals with differen …
Programmed versus non-programmed evolution of aging. What is the evidence?
Pamplona R, Jové M, Gómez J, Barja G. Pamplona R, et al. Among authors: barja g. Exp Gerontol. 2023 May;175:112162. doi: 10.1016/j.exger.2023.112162. Epub 2023 Apr 5. Exp Gerontol. 2023. PMID: 37004927 Free article. Review.
These theories may be grouped into those that defend non-programmed aging (non-PA) and those that propose the existence of programmed aging (PA). In the present article we examine many observational and experimental data from both the field and from the laboratory a …
These theories may be grouped into those that defend non-programmed aging (non-PA) and those that propose the existence of programmed …
Phenotypic molecular features of long-lived animal species.
Jové M, Mota-Martorell N, Fernàndez-Bernal A, Portero-Otin M, Barja G, Pamplona R. Jové M, et al. Among authors: barja g. Free Radic Biol Med. 2023 Nov 1;208:728-747. doi: 10.1016/j.freeradbiomed.2023.09.023. Epub 2023 Sep 23. Free Radic Biol Med. 2023. PMID: 37748717 Free article. Review.
Whole organism aging: Parabiosis, inflammaging, epigenetics, and peripheral and central aging clocks. The ARS of aging.
Pamplona R, Jové M, Gómez J, Barja G. Pamplona R, et al. Among authors: barja g. Exp Gerontol. 2023 Apr;174:112137. doi: 10.1016/j.exger.2023.112137. Epub 2023 Mar 9. Exp Gerontol. 2023. PMID: 36871903 Free article. Review.
The strong interest shown in the study of the causes of aging in recent decades has uncovered many mechanisms that could contribute to the rate of aging. ...In this article we focus on less known extracellular, systemic, and whole organism level mechanisms that coul …
The strong interest shown in the study of the causes of aging in recent decades has uncovered many mechanisms that could contribute t …
The mitochondrial free radical theory of aging.
Barja G. Barja G. Prog Mol Biol Transl Sci. 2014;127:1-27. doi: 10.1016/B978-0-12-394625-6.00001-5. Prog Mol Biol Transl Sci. 2014. PMID: 25149212 Review.
The mitochondrial free radical theory of aging is reviewed. Only two parameters currently correlate with species longevity in the right sense: the mitochondrial rate of reactive oxygen species (mitROS) production and the degree of fatty acid unsaturation of tissue membrane …
The mitochondrial free radical theory of aging is reviewed. Only two parameters currently correlate with species longevity in the rig …
mTORC1 is also involved in longevity between species.
Barja G, Pamplona R. Barja G, et al. Aging (Albany NY). 2021 May 29;13(11):14544-14545. doi: 10.18632/aging.203129. Epub 2021 May 29. Aging (Albany NY). 2021. PMID: 34057907 Free PMC article. No abstract available.
[Calorie restriction, oxidative stress and longevity].
López-Torres M, Barja G. López-Torres M, et al. Among authors: barja g. Rev Esp Geriatr Gerontol. 2008 Jul-Aug;43(4):252-60. doi: 10.1016/s0211-139x(08)71190-9. Rev Esp Geriatr Gerontol. 2008. PMID: 18682147 Free article. Review. Spanish.
Studies on the relationship between oxidative stress and ageing in different vertebrate species and in calorie-restricted animals are reviewed. ...The available evidence shows that long-living vertebrates consistently have low rates of mitochondrial free radical generation …
Studies on the relationship between oxidative stress and ageing in different vertebrate species and in calorie-restricted animals are …
58 results