Towards a unified mechanistic theory of aging.
Barja G.
Barja G.
Exp Gerontol. 2019 Sep;124:110627. doi: 10.1016/j.exger.2019.05.016. Epub 2019 Jun 5.
Exp Gerontol. 2019.
PMID: 31173843
Review.
Aging effectors include mitROS production, lipid unsaturation, autophagy, mitochondrial DNA repair and possibly others like apoptosis, proteostasis, or telomere shortening, corresponding to different classic theories of aging. ...The aging regulating system r …
Aging effectors include mitROS production, lipid unsaturation, autophagy, mitochondrial DNA repair and possibly others like apoptosis …