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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2001 2
2003 1
2007 1
2008 1
2009 2
2010 3
2011 3
2012 9
2013 7
2014 1
2016 4
2017 7
2018 1
2019 3
2020 2
2021 1
2023 2
2024 0

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46 results

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Page 1
STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts.
Buckbinder L, St Jean DJ Jr, Tieu T, Ladd B, Hilbert B, Wang W, Alltucker JT, Manimala S, Kryukov GV, Brooijmans N, Dowdell G, Jonsson P, Huff M, Guzman-Perez A, Jackson EL, Goncalves MD, Stuart DD. Buckbinder L, et al. Among authors: guzman perez a. Cancer Discov. 2023 Nov 1;13(11):2432-2447. doi: 10.1158/2159-8290.CD-23-0396. Cancer Discov. 2023. PMID: 37623743 Free PMC article.
Pituitary dysfunction in granulomatosis with polyangiitis.
Vega-Beyhart A, Medina-Rangel IR, Hinojosa-Azaola A, Fernández-Barrio M, Vargas-Castro AS, García-Inciarte L, Guzmán-Pérez A, Torres-Victoria TR, Martínez-Sánchez FD, Pérez-Guzmán MC, Hinojosa-Amaya JM, León-Suárez A, Gómez-Sámano MA, Gómez-Pérez FJ, Cuevas-Ramos D. Vega-Beyhart A, et al. Among authors: guzman perez a. Clin Rheumatol. 2020 Feb;39(2):595-606. doi: 10.1007/s10067-019-04735-7. Epub 2019 Aug 24. Clin Rheumatol. 2020. PMID: 31446541 Review.
Increased building block access through collaboration.
Helal CJ, Bartolozzi A, Goble SD, Mani NS, Guzman-Perez A, Ohri AK, Shi ZC, Subramanyam C. Helal CJ, et al. Among authors: guzman perez a. Drug Discov Today. 2018 Aug;23(8):1458-1462. doi: 10.1016/j.drudis.2018.03.001. Epub 2018 Mar 20. Drug Discov Today. 2018. PMID: 29571837 Review. No abstract available.
Analyzing Learned Molecular Representations for Property Prediction.
Yang K, Swanson K, Jin W, Coley C, Eiden P, Gao H, Guzman-Perez A, Hopper T, Kelley B, Mathea M, Palmer A, Settels V, Jaakkola T, Jensen K, Barzilay R. Yang K, et al. Among authors: guzman perez a. J Chem Inf Model. 2019 Aug 26;59(8):3370-3388. doi: 10.1021/acs.jcim.9b00237. Epub 2019 Aug 13. J Chem Inf Model. 2019. PMID: 31361484 Free PMC article.
Discovery of 6-Oxo-4-phenyl-hexanoic acid derivatives as RORγt inverse agonists showing favorable ADME profile.
Nakajima R, Oono H, Kumazawa K, Ida T, Hirata J, White RD, Min X, Guzman-Perez A, Wang Z, Symons A, Singh SK, Mothe SR, Belyakov S, Chakrabarti A, Shuto S. Nakajima R, et al. Among authors: guzman perez a. Bioorg Med Chem Lett. 2021 Mar 15;36:127786. doi: 10.1016/j.bmcl.2021.127786. Epub 2021 Jan 23. Bioorg Med Chem Lett. 2021. PMID: 33493627
Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors.
Schenkel LB, DiMauro EF, Nguyen HN, Chakka N, Du B, Foti RS, Guzman-Perez A, Jarosh M, La DS, Ligutti J, Milgram BC, Moyer BD, Peterson EA, Roberts J, Yu VL, Weiss MM. Schenkel LB, et al. Among authors: guzman perez a. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3817-3824. doi: 10.1016/j.bmcl.2017.06.054. Epub 2017 Jun 26. Bioorg Med Chem Lett. 2017. PMID: 28684121
Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists.
Nakajima R, Oono H, Sugiyama S, Matsueda Y, Ida T, Kakuda S, Hirata J, Baba A, Makino A, Matsuyama R, White RD, Wurz RΡ, Shin Y, Min X, Guzman-Perez A, Wang Z, Symons A, Singh SK, Mothe SR, Belyakov S, Chakrabarti A, Shuto S. Nakajima R, et al. Among authors: guzman perez a. ACS Med Chem Lett. 2020 Feb 27;11(4):528-534. doi: 10.1021/acsmedchemlett.9b00649. eCollection 2020 Apr 9. ACS Med Chem Lett. 2020. PMID: 32292560 Free PMC article.
Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities.
Weiss MM, Dineen TA, Marx IE, Altmann S, Boezio A, Bregman H, Chu-Moyer M, DiMauro EF, Feric Bojic E, Foti RS, Gao H, Graceffa R, Gunaydin H, Guzman-Perez A, Huang H, Huang L, Jarosh M, Kornecook T, Kreiman CR, Ligutti J, La DS, Lin MJ, Liu D, Moyer BD, Nguyen HN, Peterson EA, Rose PE, Taborn K, Youngblood BD, Yu V, Fremeau RT Jr. Weiss MM, et al. Among authors: guzman perez a. J Med Chem. 2017 Jul 27;60(14):5969-5989. doi: 10.1021/acs.jmedchem.6b01851. Epub 2017 Apr 20. J Med Chem. 2017. PMID: 28287723
Pyrimidone-based series of glucokinase activators with alternative donor-acceptor motif.
Filipski KJ, Guzman-Perez A, Bian J, Perreault C, Aspnes GE, Didiuk MT, Dow RL, Hank RF, Jones CS, Maguire RJ, Tu M, Zeng D, Liu S, Knafels JD, Litchfield J, Atkinson K, Derksen DR, Bourbonais F, Gajiwala KS, Hickey M, Johnson TO, Humphries PS, Pfefferkorn JA. Filipski KJ, et al. Among authors: guzman perez a. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4571-8. doi: 10.1016/j.bmcl.2013.06.036. Epub 2013 Jun 20. Bioorg Med Chem Lett. 2013. PMID: 23831135
46 results