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32 results

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Page 1
CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice.
Hammerschmidt P, Steculorum SM, Bandet CL, Del Río-Martín A, Steuernagel L, Kohlhaas V, Feldmann M, Varela L, Majcher A, Quatorze Correia M, Klar RFU, Bauder CA, Kaya E, Porniece M, Biglari N, Sieben A, Horvath TL, Hornemann T, Brodesser S, Brüning JC. Hammerschmidt P, et al. Nat Commun. 2023 Nov 29;14(1):7824. doi: 10.1038/s41467-023-42595-7. Nat Commun. 2023. PMID: 38016943 Free PMC article.
Mn-Mediated Direct Regioselective C-H Trifluoromethylation of Imidazopyridines and Quinoxalines.
Firuz ME, Rajai-Daryasarei S, Rominger F, Biglari A, Balalaie S. Firuz ME, et al. J Org Chem. 2023 Aug 4;88(15):10599-10608. doi: 10.1021/acs.joc.3c00621. Epub 2023 Jul 20. J Org Chem. 2023. PMID: 37471701
A simple and highly efficient strategy has been developed for direct C-H trifluoromethylation at C-3 of imidazopyridines and C-8 of quinoxalines with readily available Langlois reagent through KMnO(4)/AcOH system. ...
A simple and highly efficient strategy has been developed for direct C-H trifluoromethylation at C-3 of imidazopyridines and C-8 of q …
Serum sCD95L concentration in patients with spinal cord injury.
Biglari B, Büchler A, Swing T, Child C, Biehl E, Reitzel T, Bruckner T, Ferbert T, Korff S, Rief H, Gerner HJ, Moghaddam A. Biglari B, et al. J Int Med Res. 2015 Apr;43(2):250-6. doi: 10.1177/0300060514559794. Epub 2015 Jan 19. J Int Med Res. 2015. PMID: 25601970 Free article.
Blood was collected on admission to hospital and at 4 h, 9 h, 12 h, 24 h, 3 days, 7 days, and 2, 4, 8 and 12 weeks postadmission. Serum concentrations of sCD95L were determined via immunoassay. ...Mean sCD95L concentrations were significantly lower at …
Blood was collected on admission to hospital and at 4 h, 9 h, 12 h, 24 h, 3 days, 7 days, and 2, 4, 8 and 12 wee …
sCD95L in serum after spinal cord injury.
Moghaddam A, Sperl A, Heller R, Gerner HJ, Biglari B. Moghaddam A, et al. Spinal Cord. 2016 Nov;54(11):957-960. doi: 10.1038/sc.2016.44. Epub 2016 Apr 19. Spinal Cord. 2016. PMID: 27089864
Blood was collected on post-admission and according to a fixed scheme, that is, after 4, 9, 12 h, 1, 3 days and 1, 2, 4, 8, 12 weeks. RESULTS: By comparing G1 with G2, we found a correlation between neurological remission and sCD95L serum concentrations. Consistently eleva …
Blood was collected on post-admission and according to a fixed scheme, that is, after 4, 9, 12 h, 1, 3 days and 1, 2, 4, 8, 12 weeks. …
Zinc Concentration Dynamics Indicate Neurological Impairment Odds after Traumatic Spinal Cord Injury.
Heller RA, Sperl A, Seelig J, Haubruck P, Bock T, Werner T, Besseling A, Sun Q, Schomburg L, Moghaddam A, Biglari B. Heller RA, et al. Antioxidants (Basel). 2020 May 13;9(5):421. doi: 10.3390/antiox9050421. Antioxidants (Basel). 2020. PMID: 32414139 Free PMC article.
Serum samples were collected at five different points in time after injury (at admission, and after 4 h, 9 h, 12 h, 24 h, and 3 d). The analysis of the serum Zn concentrations was conducted by total reflection X-ray fluorescence (TXRF). ...The median Z …
Serum samples were collected at five different points in time after injury (at admission, and after 4 h, 9 h, 12 h, 24 …
Predicting neurological recovery after traumatic spinal cord injury by time-resolved analysis of monocyte subsets.
Heller RA, Seelig J, Crowell HL, Pilz M, Haubruck P, Sun Q, Schomburg L, Daniel V, Moghaddam A, Biglari B. Heller RA, et al. Brain. 2021 Nov 29;144(10):3159-3174. doi: 10.1093/brain/awab203. Brain. 2021. PMID: 34022039
Blood samples were drawn at admission and 4 h, 9 h, 12 h, 1 and 3 days as well as 1 and 2 weeks and 1, 2 and 3 months after the trauma. ...In the elastic net regularized model, we identified an association between the increase of a subpopulation of intermedia …
Blood samples were drawn at admission and 4 h, 9 h, 12 h, 1 and 3 days as well as 1 and 2 weeks and 1, 2 and 3 months a …
The Fat Mass and Obesity-Associated Protein (FTO) Regulates Locomotor Responses to Novelty via D2R Medium Spiny Neurons.
Ruud J, Alber J, Tokarska A, Engström Ruud L, Nolte H, Biglari N, Lippert R, Lautenschlager Ä, Cieślak PE, Szumiec Ł, Hess ME, Brönneke HS, Krüger M, Nissbrandt H, Korotkova T, Silberberg G, Rodriguez Parkitna J, Brüning JC. Ruud J, et al. Cell Rep. 2019 Jun 11;27(11):3182-3198.e9. doi: 10.1016/j.celrep.2019.05.037. Cell Rep. 2019. PMID: 31189104 Free article.
32 results