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Page 1
Macrophages, reactive nitrogen species, and lung injury.
Laskin DL, Sunil VR, Fakhrzadeh L, Groves A, Gow AJ, Laskin JD. Laskin DL, et al. Ann N Y Acad Sci. 2010 Aug;1203:60-5. doi: 10.1111/j.1749-6632.2010.05607.x. Ann N Y Acad Sci. 2010. PMID: 20716284 Free PMC article. Review.
Inhaled nitric oxide primes lung macrophages to produce reactive oxygen and nitrogen intermediates.
Weinberger B, Fakhrzadeh L, Heck DE, Laskin JD, Gardner CR, Laskin DL. Weinberger B, et al. Am J Respir Crit Care Med. 1998 Sep;158(3):931-8. doi: 10.1164/ajrccm.158.3.9708014. Am J Respir Crit Care Med. 1998. PMID: 9731028
Whereas inhalation of nitric oxide (10 to 100 ppm, 5 h) by Balb/c mice had no effect on the number or type of cells recovered from the lung, a dose-related increase in bronchoalveolar lavage protein was observed, suggesting that nitric oxide induces alveolar epithelial inj …
Whereas inhalation of nitric oxide (10 to 100 ppm, 5 h) by Balb/c mice had no effect on the number or type of cells recovered from th …
Superoxide dismutase-overexpressing mice are resistant to ozone-induced tissue injury and increases in nitric oxide and tumor necrosis factor-alpha.
Fakhrzadeh L, Laskin JD, Gardner CR, Laskin DL. Fakhrzadeh L, et al. Am J Respir Cell Mol Biol. 2004 Mar;30(3):280-7. doi: 10.1165/rcmb.2003-0044OC. Epub 2003 Jul 10. Am J Respir Cell Mol Biol. 2004. PMID: 12855403
Treatment of wild-type mice with ozone (0.8 ppm, 3 h) resulted in increased bronchoalveolar lavage fluid protein, which was maximal after 24-48 h. ...
Treatment of wild-type mice with ozone (0.8 ppm, 3 h) resulted in increased bronchoalveolar lavage fluid protein, which was maximal a …
Analyzing the Association of Social Capital and Sleep Quality of the Elderly Community.
Mohammadi M, Mohammadnabizadeh S, Varmaghani M, Moodi M, Shrifi F, Shirazinia M, Fakhrzadeh H, Payab M, Khorashadizadeh M, Naderimagham S. Mohammadi M, et al. Health Sci Rep. 2025 May 19;8(5):e70766. doi: 10.1002/hsr2.70766. eCollection 2025 May. Health Sci Rep. 2025. PMID: 40391259 Free PMC article.
These results also show that the social capital in the group that sleeps more than 6 h is stronger than the group that sleeps less than 6 h. Also, married people in each group with less sleep (RR = 0.92) or more than 6 h (RR = 0.66) had a better condition tha …
These results also show that the social capital in the group that sleeps more than 6 h is stronger than the group that sleeps less th …
Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-alpha following ozone inhalation.
Fakhrzadeh L, Laskin JD, Laskin DL. Fakhrzadeh L, et al. Toxicol Appl Pharmacol. 2008 Mar 15;227(3):380-9. doi: 10.1016/j.taap.2007.11.012. Epub 2007 Nov 22. Toxicol Appl Pharmacol. 2008. PMID: 18207479 Free PMC article.
Treatment of wild type (WT) mice with ozone (0.8 ppm, 3 h) resulted in a rapid increase in NF-kappaB binding activity in AM, which persisted for at least 12 h. ...
Treatment of wild type (WT) mice with ozone (0.8 ppm, 3 h) resulted in a rapid increase in NF-kappaB binding activity in AM, which pe …
Ozone-induced production of nitric oxide and TNF-alpha and tissue injury are dependent on NF-kappaB p50.
Fakhrzadeh L, Laskin JD, Laskin DL. Fakhrzadeh L, et al. Am J Physiol Lung Cell Mol Physiol. 2004 Aug;287(2):L279-85. doi: 10.1152/ajplung.00348.2003. Epub 2004 Apr 2. Am J Physiol Lung Cell Mol Physiol. 2004. PMID: 15064226 Free article.
Treatment of wild-type (WT) mice with ozone (0.8 ppm, 3 h) resulted in a rapid increase in NF-kappaB binding activity in alveolar macrophages that peaked after 6-12 h. ...
Treatment of wild-type (WT) mice with ozone (0.8 ppm, 3 h) resulted in a rapid increase in NF-kappaB binding activity in alveolar mac …
Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and tissue injury.
Fakhrzadeh L, Laskin JD, Laskin DL. Fakhrzadeh L, et al. Am J Respir Cell Mol Biol. 2002 Apr;26(4):413-9. doi: 10.1165/ajrcmb.26.4.4516. Am J Respir Cell Mol Biol. 2002. PMID: 11919077
Treatment of wild-type control mice with ozone (0.8 ppm) for 3 h resulted in a time-dependent increase in protein and cells in bronchoalveolar lavage fluid, which reached a maximum 24-48 h after exposure. ...
Treatment of wild-type control mice with ozone (0.8 ppm) for 3 h resulted in a time-dependent increase in protein and cells in bronch …
Association between vitamin D deficiency and general and abdominal obesity in older adults: insights from baseline data of the Birjand Longitudinal Aging Study (BLAS).
Varmaghani M, Tajik A, Movahedi Aliabadi M, Mohammadi M, Shobeiri N, Soleimanzadeh M, Fakhrzadeh H, Payab M, Ebrahimpour M, Moudi M, Khorashadizadeh M, Sharifi F. Varmaghani M, et al. J Diabetes Metab Disord. 2025 Nov 17;24(2):271. doi: 10.1007/s40200-025-01784-5. eCollection 2025 Dec. J Diabetes Metab Disord. 2025. PMID: 41262624
Blood samples were taken after at least 12 h of fasting to measure serum 25(OH)D levels. The significance level was set at < 0.1. ...

Blood samples were taken after at least 12 h of fasting to measure serum 25(OH)D levels. The significance level was set at < 0.1.

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Upregulation of phosphoinositide 3-kinase and protein kinase B in alveolar macrophages following ozone inhalation. Role of NF-kappaB and STAT-1 in ozone-induced nitric oxide production and toxicity.
Laskin DL, Fakhrzadeh L, Heck DE, Gerecke D, Laskin JD. Laskin DL, et al. Mol Cell Biochem. 2002 May-Jun;234-235(1-2):91-8. Mol Cell Biochem. 2002. PMID: 12162464
Treatment of mice with ozone (0.8 ppm, 3 h) resulted in increased expression of inducible nitric oxide synthase (iNOS) protein and production of nitric oxide (NO) and peroxynitrite by alveolar macrophages. ...
Treatment of mice with ozone (0.8 ppm, 3 h) resulted in increased expression of inducible nitric oxide synthase (iNOS) protein and pr …