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A 52-Year-Old Man With Chest Pain and Dyspnea.
Murphy CG, Goldstein JM, Besharati S, Kobsa S, Salvatore MM, Rosenzweig EB, Ingham M, Del Portillo A, Takeda K, Chandra S, Furfaro D. Murphy CG, et al. Chest. 2022 Nov;162(5):e259-e264. doi: 10.1016/j.chest.2022.05.020. Chest. 2022. PMID: 36344135 Free PMC article.
LIN28B induces a differentiation program through CDX2 in colon cancer.
Suzuki K, Masuike Y, Mizuno R, Sachdeva UM, Chatterji P, Andres SF, Sun W, Klein-Szanto AJ, Besharati S, Remotti HE, Verzi MP, Rustgi AK. Suzuki K, et al. JCI Insight. 2021 May 10;6(9):e140382. doi: 10.1172/jci.insight.140382. JCI Insight. 2021. PMID: 33755595 Free PMC article.
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
Tomkovich S, Dejea CM, Winglee K, Drewes JL, Chung L, Housseau F, Pope JL, Gauthier J, Sun X, Mühlbauer M, Liu X, Fathi P, Anders RA, Besharati S, Perez-Chanona E, Yang Y, Ding H, Wu X, Wu S, White JR, Gharaibeh RZ, Fodor AA, Wang H, Pardoll DM, Jobin C, Sears CL. Tomkovich S, et al. J Clin Invest. 2019 Mar 11;129(4):1699-1712. doi: 10.1172/JCI124196. eCollection 2019 Mar 11. J Clin Invest. 2019. PMID: 30855275 Free PMC article.
Phase I Study of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors (ETCTN-9844).
Roussos Torres ET, Rafie C, Wang C, Lim D, Brufsky A, LoRusso P, Eder JP, Chung V, Downs M, Geare M, Piekarz R, Streicher H, Anforth L, Rudek MA, Zhu Q, Besharati S, Cimino-Mathews A, Anders RA, Stearns V, Jaffee EM, Connolly RM. Roussos Torres ET, et al. Clin Cancer Res. 2021 Nov 1;27(21):5828-5837. doi: 10.1158/1078-0432.CCR-20-5017. Epub 2021 Jun 16. Clin Cancer Res. 2021. PMID: 34135021 Free PMC article.
Bacterial-Driven Inflammation and Mutant BRAF Expression Combine to Promote Murine Colon Tumorigenesis That Is Sensitive to Immune Checkpoint Therapy.
DeStefano Shields CE, White JR, Chung L, Wenzel A, Hicks JL, Tam AJ, Chan JL, Dejea CM, Fan H, Michel J, Maiuri AR, Sriramkumar S, Podicheti R, Rusch DB, Wang H, De Marzo AM, Besharati S, Anders RA, Baylin SB, O'Hagan HM, Housseau F, Sears CL. DeStefano Shields CE, et al. Cancer Discov. 2021 Jul;11(7):1792-1807. doi: 10.1158/2159-8290.CD-20-0770. Epub 2021 Feb 25. Cancer Discov. 2021. PMID: 33632774 Free PMC article.