The HLA-B -21 M/T dimorphism associates with disease severity in COVID-19.
Strunz B, Momayyezi P, Bilev E, Muvva JR, Chen P, Bister J, Schaffer M, Akber M, Cornillet M; Karolinska KI/K COVID-19 Study Group; Horowitz A, Malmberg KJ, Rooyackers O, Aleman S, Ljunggren HG, Björkström NK, Strålin K, Hammer Q.
Strunz B, et al.
Genes Immun. 2025 Feb;26(1):70-74. doi: 10.1038/s41435-024-00302-6. Epub 2024 Nov 1.
Genes Immun. 2025.
PMID: 39487235
Free PMC article.
We found that HLA-B -21 M/M genotypes were more prevalent in patients with moderate compared to severe COVID-19 (6.0% vs. 0.9%). Comparison of age- and sex-matched sub-groups revealed that patients with M/M genotypes required mechanical respiratory sup …
We found that HLA-B -21 M/M genotypes were more prevalent in patients with moderate compared to severe COVID-19 (6.0% vs. 0.9% …