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Page 1
Hippocampal neuroprotection mediated by secretome of human mesenchymal stem cells against experimental stroke.
Asgari Taei A, Dargahi L, Khodabakhsh P, Kadivar M, Farahmandfar M. Asgari Taei A, et al. CNS Neurosci Ther. 2022 Sep;28(9):1425-1438. doi: 10.1111/cns.13886. Epub 2022 Jun 18. CNS Neurosci Ther. 2022. PMID: 35715988 Free PMC article.
METHODS: Ischemic stroke was induced by right middle cerebral artery occlusion (MCAO) in male Wistar rats, and CM was infused either one time (1-h post-stroke; CM1) or three times (1-, 24-, and 48-h post-stroke; CM3) into left lateral ventricle. ...
METHODS: Ischemic stroke was induced by right middle cerebral artery occlusion (MCAO) in male Wistar rats, and CM was infused either one tim …
Fingolimod increases oligodendrocytes markers expression in epidermal neural crest stem cells.
Pournajaf S, Valian N, Mohaghegh Shalmani L, Khodabakhsh P, Jorjani M, Dargahi L. Pournajaf S, et al. Eur J Pharmacol. 2020 Oct 15;885:173502. doi: 10.1016/j.ejphar.2020.173502. Epub 2020 Aug 26. Eur J Pharmacol. 2020. PMID: 32860811
The cell viability was evaluated by MTT assay at 6, 24 and 72 h. The expression of neurotrophic and differentiation factors in the cells treated with 100 and 400 nM fingolimod were measured at 24 and 120 h. Fingolimod at 50-600 nM increased the cells viability after …
The cell viability was evaluated by MTT assay at 6, 24 and 72 h. The expression of neurotrophic and differentiation factors in the ce …
Degradation of azo dye Acid Red 14 (AR14) from aqueous solution using H(2) O(2) /nZVI and S(2) O(8) (2-) /nZVI processes in the presence of UV irradiation.
Samarghandi MR, Dargahi A, Zolghadr Nasab H, Ghahramani E, Salehi S. Samarghandi MR, et al. Water Environ Res. 2020 Aug;92(8):1173-1183. doi: 10.1002/wer.1312. Epub 2020 Apr 12. Water Environ Res. 2020. PMID: 32073695
However, a too high oxidant concentration (H(2) O(2) and S(2) O(4) (2-) ) could inhibit the degradation. The experimental conditions for degradation of AR14 by UV/S(2) O(8) (2-) /nZVI and UV/H(2) O(2) /nZVI processes were as follows: [H(2) O(2) ] = 10 mM, [S( …
However, a too high oxidant concentration (H(2) O(2) and S(2) O(4) (2-) ) could inhibit the degradation. The experimental conditions …
Effect of methamphetamine on rat primary midbrain cells; mitochondrial biogenesis as a compensatory response.
Valian N, Heravi M, Ahmadiani A, Dargahi L. Valian N, et al. Neuroscience. 2019 May 15;406:278-289. doi: 10.1016/j.neuroscience.2019.03.016. Epub 2019 Mar 15. Neuroscience. 2019. PMID: 30885640
Primary mesencephalon cells prepared from E14.5 rat embryo were treated with 0.2-5 mM MA concentrations for 24, 48, and 72 h. Morphological changes of the cells were observed under light microscope. Cell viability and cell death following MA were assessed using MTT assay a …
Primary mesencephalon cells prepared from E14.5 rat embryo were treated with 0.2-5 mM MA concentrations for 24, 48, and 72 h. Morphol …
Yttrium oxide nanoparticles alleviate cognitive deficits, neuroinflammation, and mitochondrial biogenesis impairment induced by streptozotocin.
Baghaee P, Yoonesi M, Esfahani DE, Beirami E, Dargahi L, Rashidi FS, Valian N. Baghaee P, et al. Neurosci Lett. 2024 Aug 10;837:137895. doi: 10.1016/j.neulet.2024.137895. Epub 2024 Jul 19. Neurosci Lett. 2024. PMID: 39025434
Intraperitoneal treatment with Y(2)O(3)NPs (0.1, 0.3, or 0.5 mg/kg) was started 24 h after the STZ injection and continued for 21 days. The mRNA and protein levels of pro-inflammatory cytokines (TNF-alpha, IL-6, and IL-1beta) and components involved in mitochondrial biogen …
Intraperitoneal treatment with Y(2)O(3)NPs (0.1, 0.3, or 0.5 mg/kg) was started 24 h after the STZ injection and continued for 21 day …
The Auditory Brainstem Response (ABR) Test, Supplementary to Behavioral Tests for Evaluation of the Salicylate-Induced Tinnitus.
Rezapour M, Akbari M, Dargahi L, Zibaii MI, Shahbazi A. Rezapour M, et al. Indian J Otolaryngol Head Neck Surg. 2023 Apr;75(Suppl 1):6-15. doi: 10.1007/s12070-022-03117-x. Epub 2022 Aug 4. Indian J Otolaryngol Head Neck Surg. 2023. PMID: 37206728 Free PMC article.
The rats were evaluated by pre-pulse inhibition (PPI), gap pre-pulse inhibition of the acoustic startle (GPIAS), and ABR tests, at baseline, 14 and 62 h after salicylate (350 mg/kg) or vehicle injection. The mean percentage of GPIAS test was significantly reduced following …
The rats were evaluated by pre-pulse inhibition (PPI), gap pre-pulse inhibition of the acoustic startle (GPIAS), and ABR tests, at baseline, …
Insulin Promotes Schwann-Like Cell Differentiation of Rat Epidermal Neural Crest Stem Cells.
Khodabakhsh P, Pournajaf S, Mohaghegh Shalmani L, Ahmadiani A, Dargahi L. Khodabakhsh P, et al. Mol Neurobiol. 2021 Oct;58(10):5327-5337. doi: 10.1007/s12035-021-02423-9. Epub 2021 Jul 23. Mol Neurobiol. 2021. PMID: 34297315
The viability of cells treated with a range of insulin concentrations (0.05-100 mug/ml) was defined by MTT assay at 24, 48, and 72 h. The gene expression profiles of neurotrophic factors (BDNF, FGF-2, and IL-6), key regulators involved in the development of SC (EGR-1, SOX- …
The viability of cells treated with a range of insulin concentrations (0.05-100 mug/ml) was defined by MTT assay at 24, 48, and 72 h. …
Intranasal insulin improves mitochondrial function and attenuates motor deficits in a rat 6-OHDA model of Parkinson's disease.
Iravanpour F, Dargahi L, Rezaei M, Haghani M, Heidari R, Valian N, Ahmadiani A. Iravanpour F, et al. CNS Neurosci Ther. 2021 Mar;27(3):308-319. doi: 10.1111/cns.13609. Epub 2021 Jan 26. CNS Neurosci Ther. 2021. PMID: 33497031 Free PMC article.
METHODS: Rats were treated with a daily low dose (4IU/day) of IN insulin, starting 72 h after 6-OHDA-induced lesion and continued for 14 days. Motor performance, dopaminergic cell survival, mitochondrial dehydrogenases activity, mitochondrial swelling, mitochondria permeab …
METHODS: Rats were treated with a daily low dose (4IU/day) of IN insulin, starting 72 h after 6-OHDA-induced lesion and continued for …
Enhancing the expression of neurotrophic factors in epidermal neural crest stem cells by valproic acid: A potential candidate for combinatorial treatment.
Pandamooz S, Salehi MS, Safari A, Azarpira N, Heravi M, Ahmadiani A, Dargahi L. Pandamooz S, et al. Neurosci Lett. 2019 Jun 21;704:8-14. doi: 10.1016/j.neulet.2019.03.033. Epub 2019 Mar 20. Neurosci Lett. 2019. PMID: 30904572
Finally, stem cells were treated with 0.1 and 1 mM VPA and the drug impact on the transcription level of BDNF, GDNF, VEGF, NGF and NT3 at 6, 24, 72, 168 h was assessed by quantitative real-time PCR. The examined proteins expressions in the population of migrated cells conf …
Finally, stem cells were treated with 0.1 and 1 mM VPA and the drug impact on the transcription level of BDNF, GDNF, VEGF, NGF and NT3 at 6, …
Imipramine alleviates memory impairment and hippocampal apoptosis in STZ-induced sporadic Alzheimer's rat model: Possible contribution of MAPKs and insulin signaling.
Javadpour P, Askari S, Rashidi FS, Dargahi L, Ahmadiani A, Ghasemi R. Javadpour P, et al. Behav Brain Res. 2021 Jun 25;408:113260. doi: 10.1016/j.bbr.2021.113260. Epub 2021 Mar 26. Behav Brain Res. 2021. PMID: 33775777
Pursuing this objective, rats were treated with imipramine 10 or 20 mg/kg i.p. once a day for 14 days. 24 h after the last injection, memory function was evaluated by the Morris water maze (MWM) test in 4 consecutive days. ...
Pursuing this objective, rats were treated with imipramine 10 or 20 mg/kg i.p. once a day for 14 days. 24 h after the last injection, …
33 results