H&E-based MSI/MMR testing with AI in colorectal cancer: a multi-centred blinded evaluation.
Bass C, Ntelemis F, Schmidt J, Wolf S, Geraldes A, Mehrotra D, Singhal S, Kumar N, Marcia A, Bennett N, Maiques O, Hyde M, Mistry B, Rogerson G, Cummings M, Freer C, Walsh E, Salto-Tellez M, Loughrey M, Um IH, Harrison DJ, Clarkson R, Blackwood J, Barrett JC, Kather JN, Orsi NM, Pandya P, Arslan S.
Bass C, et al.
NPJ Digit Med. 2025 Dec 15;9(1):44. doi: 10.1038/s41746-025-02218-5.
NPJ Digit Med. 2025.
PMID: 41398057
Free PMC article.
PANProfiler Colorectal (PPC) is an artificial intelligence (AI)-based biomarker test that determines MSI/MMR status directly from haematoxylin and eosin (H&E)-stained slides. We conducted a blinded, multi-centred validation to assess PPC's performance against standard …
PANProfiler Colorectal (PPC) is an artificial intelligence (AI)-based biomarker test that determines MSI/MMR status directly from haematoxyl …