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Showing results for H. ourai
Your search for H. Ouraji retrieved no results
Inhibition of GAPDH aggregation as a potential treatment for acute ischemic stroke.
Itakura M, Kubo T, Kaneshige A, Nakatsuji M, Harada N, Yamaji R, Hikida T, Inui T, Nakajima H. Itakura M, et al. iScience. 2025 May 2;28(6):112564. doi: 10.1016/j.isci.2025.112564. eCollection 2025 Jun 20. iScience. 2025. PMID: 40487448 Free PMC article.
Furthermore, GAPDH aggregation inhibitor peptide-17, developed by our peptide-screening-methods, ameliorated brain infarction and neurological deficits, even after 6 h of reperfusion. These findings suggest that inhibition of GAPDH aggregation may be a potential therapeuti …
Furthermore, GAPDH aggregation inhibitor peptide-17, developed by our peptide-screening-methods, ameliorated brain infarction and neurologic …
Zinc Potentiates Lipopolysaccharide-induced Nitric Oxide Production in Cultured Primary Rat Astrocytes.
Moriyama M, Fujitsuka S, Kawabe K, Takano K, Nakamura Y. Moriyama M, et al. Neurochem Res. 2018 Feb;43(2):363-374. doi: 10.1007/s11064-017-2431-5. Epub 2017 Nov 9. Neurochem Res. 2018. PMID: 29124566
Zn(2+) enhanced the phosphorylation of p38-mitogen-activated protein kinase (MAPK) at 1-6 h after LPS treatment. The LPS-induced nuclear factor-kappaB (NFkappaB) activation was sustained for 6 h by Zn(2+). ...
Zn(2+) enhanced the phosphorylation of p38-mitogen-activated protein kinase (MAPK) at 1-6 h after LPS treatment. The LPS-induced nucl …
Acetate Attenuates Lipopolysaccharide-Induced Nitric Oxide Production Through an Anti-Oxidative Mechanism in Cultured Primary Rat Astrocytes.
Moriyama M, Kurebayashi R, Kawabe K, Takano K, Nakamura Y. Moriyama M, et al. Neurochem Res. 2016 Nov;41(11):3138-3146. doi: 10.1007/s11064-016-2038-2. Epub 2016 Aug 20. Neurochem Res. 2016. PMID: 27542961
Acetate suppressed the phosphorylation of p38-mitogen-activated protein kinase 24 h after LPS treatment. Acetate decreased the LPS-induced production of intracellular reactive oxygen species (ROS) at 4-24 h concomitant with an increase in glutathione. ...
Acetate suppressed the phosphorylation of p38-mitogen-activated protein kinase 24 h after LPS treatment. Acetate decreased the LPS-in …
Acetaminophen-Induced Rat Hepatotoxicity Based on M1/M2-Macrophage Polarization, in Possible Relation to Damage-Associated Molecular Patterns and Autophagy.
Tsuji Y, Kuramochi M, Golbar HM, Izawa T, Kuwamura M, Yamate J. Tsuji Y, et al. Int J Mol Sci. 2020 Nov 26;21(23):8998. doi: 10.3390/ijms21238998. Int J Mol Sci. 2020. PMID: 33256230 Free PMC article.
Liver samples from six-week-old rats injected with APAP (1000 mg/kg BW, ip, once) after 15 h fasting were collected at hour 10, and on days 1, 2, 3, and 5. Liver lesions consisting of coagulation necrosis and inflammation were seen in the affected centrilobular area on day …
Liver samples from six-week-old rats injected with APAP (1000 mg/kg BW, ip, once) after 15 h fasting were collected at hour 10, and o …
An improved immunochromatographic test strip that sensitively detects heat-labile enterotoxin produced by enterotoxigenic Escherichia coli.
Fujimoto N, Inoue E, Yokomizo N, Hayashi S, Yoneyama M, Kohda T, Kusumoto M, Arimitsu H. Fujimoto N, et al. J Microbiol Methods. 2025 Dec;239:107299. doi: 10.1016/j.mimet.2025.107299. Epub 2025 Oct 16. J Microbiol Methods. 2025. PMID: 41109598
In addition, this IC test strip was able to detect LT in 6-h culture supernatants of clinical isolates from swine and human without requiring lincomycin supplementation. ...
In addition, this IC test strip was able to detect LT in 6-h culture supernatants of clinical isolates from swine and human without r …
Combinatorial measurement of CDKN1A/p21 and KIF20A expression for discrimination of DNA damage-induced clastogenicity.
Sakai R, Morikawa Y, Kondo C, Oka H, Miyajima H, Kubo K, Uehara T. Sakai R, et al. Int J Mol Sci. 2014 Sep 26;15(10):17256-69. doi: 10.3390/ijms151017256. Int J Mol Sci. 2014. PMID: 25264741 Free PMC article.
Cells were exposed to each compound for 4 h, and gene expression was comprehensively examined using Affymetrix U133A microarrays. ...
Cells were exposed to each compound for 4 h, and gene expression was comprehensively examined using Affymetrix U133A microarrays. ...
Extracellular superoxide dismutase induced by dopamine in cultured astrocytes.
Takano K, Tanaka N, Kawabe K, Moriyama M, Nakamura Y. Takano K, et al. Neurochem Res. 2013 Jan;38(1):32-41. doi: 10.1007/s11064-012-0882-2. Epub 2012 Sep 15. Neurochem Res. 2013. PMID: 22983620
By means of RT-PCR, all mRNA of three isozymes of SOD could be detected; however, only EC-SOD was increased by DA exposure for 24 h, dose-dependently. The expression of EC-SOD protein and the cell-surface SOD activity in astrocytes also increased with 100 muM DA exposure. …
By means of RT-PCR, all mRNA of three isozymes of SOD could be detected; however, only EC-SOD was increased by DA exposure for 24 h, …
Extracellular superoxide dismutase in cultured astrocytes: decrease in cell-surface activity and increase in medium activity by lipopolysaccharide-stimulation.
Iitsuka I, Motoyoshi-Yamashiro A, Moriyama M, Kannan-Hayashi Y, Fujimoto Y, Takano K, Murakami K, Yoneda Y, Nakamura Y. Iitsuka I, et al. Neurochem Res. 2012 Oct;37(10):2108-16. doi: 10.1007/s11064-012-0832-z. Epub 2012 Jun 28. Neurochem Res. 2012. PMID: 22740163
When astrocytes were stimulated with lipopolysaccharide (LPS) for 12-24 h, the cell-surface SOD activity decreased to a half, whereas the activity recovered after 36-48 h. ...
When astrocytes were stimulated with lipopolysaccharide (LPS) for 12-24 h, the cell-surface SOD activity decreased to a half, whereas …
Differential micronucleus frequency in isogenic human cells deficient in DNA repair pathways is a valuable indicator for evaluating genotoxic agents and their genotoxic mechanisms.
Saha LK, Kim S, Kang H, Akter S, Choi K, Sakuma T, Yamamoto T, Sasanuma H, Hirota K, Nakamura J, Honma M, Takeda S, Dertinger S. Saha LK, et al. Environ Mol Mutagen. 2018 Jul;59(6):529-538. doi: 10.1002/em.22201. Epub 2018 May 15. Environ Mol Mutagen. 2018. PMID: 29761828
Using these isogenic TK6 cell lines, the MN test was conducted for four widely-used DNA-damaging agents: methyl methanesulfonate (MMS), hydrogen peroxide (H(2) O(2) ), gamma-rays, and mitomycin C (MMC). The frequency of micronuclei in the double strand break repair-deficie …
Using these isogenic TK6 cell lines, the MN test was conducted for four widely-used DNA-damaging agents: methyl methanesulfonate (MMS), hydr …