Immunophenotyping in pemphigus reveals a T(H)17/T(FH)17 cell-dominated immune response promoting desmoglein1/3-specific autoantibody production.
Holstein J, Solimani F, Baum C, Meier K, Pollmann R, Didona D, Tekath T, Dugas M, Casadei N, Hudemann C, Polakova A, Matthes J, Schäfer I, Yazdi AS, Eming R, Hertl M, Pfützner W, Ghoreschi K, Möbs C.
Holstein J, et al.
J Allergy Clin Immunol. 2021 Jun;147(6):2358-2369. doi: 10.1016/j.jaci.2020.11.008. Epub 2020 Nov 20.
J Allergy Clin Immunol. 2021.
PMID: 33221382
BACKGROUND: T(H)2 cells were thought to be a pivotal factor for initiation of the autoimmune blistering disease pemphigus. ...In peripheral blood, the distribution of T(H) cell and folliclular helper (T(FH)) cell subsets was analyzed by flow cytometry. ...
BACKGROUND: T(H)2 cells were thought to be a pivotal factor for initiation of the autoimmune blistering disease pemphigus. ...In peri …