Genome-wide association study of cocaine self-administration behavior in Heterogeneous Stock rats.
Lara MK, Carrette LLG, Sanches TM, Polesskaya O, Avelar A, Beeson A, Beldjoud H, Boomhower B, Brennan M, Chen D, China L, Chitre AS, Conlisk DE, Fannon M, Johnson BB, Keung E, Kimbrough A, Kononoff J, Martinez AR, Maturin L, Nguyen KM, Morgan A, Mosquera J, Othman D, Plasil SL, Ramborger J, Schweitzer P, Sedighim S, Seshie O, Shankar K, Sichel B, Simpson S, Smith LC, Sneddon EA, Tieu L, Velarde N, Zahedi S, Woods LCS, Kallupi M, de Guglielmo G, Palmer AA, George O.
Lara MK, et al.
bioRxiv [Preprint]. 2025 Jul 28:2025.07.17.660811. doi: 10.1101/2025.07.17.660811.
bioRxiv. 2025.
PMID: 40766591
Free PMC article.
Updated.
Preprint.
RESULTS: Consistent with the existing literature, these traits were phenotypically and genetically correlated and exhibited modest heritability (h(2) = 0.07 - 0.16). We identified six genome-wide significant associations. One locus on chromosome 16 was associated with the …
RESULTS: Consistent with the existing literature, these traits were phenotypically and genetically correlated and exhibited modest heritabil …