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Year Number of Results
2005 1
2008 2
2009 1
2011 1
2012 3
2013 1
2015 2
2018 1
2020 2
2021 5
2022 0
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17 results
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Page 1
The Nonclinical Disposition and PK/PD Properties of GalNAc-conjugated siRNA Are Highly Predictable and Build Confidence in Translation to Man.
Chong S, Agarwal S, Agarwal S, Aluri KC, Arciprete M, Brown C, Charisse K, Cichocki J, Fitzgerald K, Goel V, Gu Y, Guenther D, Habtemariam B, Jadhav V, Janas M, Jayaraman M, Kurz J, Li J, Liou S, Liu J, Liu X, Maclauchlin C, Maier M, Manoharan M, McDougall R, Nair J, Ramsden D, Robbie G, Schmidt K, Smith P, Theile C, Vaishnaw A, Waldron S, Wu JT, Xu Y, Zhang X, Zlatev I, Castellanos-Rizaldos E. Chong S, et al. Among authors: habtemariam b. Drug Metab Dispos. 2021 Jun 21:DMD-MR-2021-000428. doi: 10.1124/dmd.121.000428. Online ahead of print. Drug Metab Dispos. 2021. PMID: 34154993 Free article.
Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects.
Habtemariam BA, Karsten V, Attarwala H, Goel V, Melch M, Clausen VA, Garg P, Vaishnaw AK, Sweetser MT, Robbie GJ, Vest J. Habtemariam BA, et al. Clin Pharmacol Ther. 2021 Feb;109(2):372-382. doi: 10.1002/cpt.1974. Epub 2020 Aug 13. Clin Pharmacol Ther. 2021. PMID: 32599652 Clinical Trial.
Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial.
Frishberg Y, Deschênes G, Groothoff JW, Hulton SA, Magen D, Harambat J, Van't Hoff WG, Lorch U, Milliner DS, Lieske JC, Haslett P, Garg PP, Vaishnaw AK, Talamudupula S, Lu J, Habtemariam BA, Erbe DV, McGregor TL, Cochat P; study collaborators. Frishberg Y, et al. Among authors: habtemariam ba. Clin J Am Soc Nephrol. 2021 Jul;16(7):1025-1036. doi: 10.2215/CJN.14730920. Epub 2021 May 13. Clin J Am Soc Nephrol. 2021. PMID: 33985991
Pharmacokinetic and Pharmacodynamic Properties of Cemdisiran, an RNAi Therapeutic Targeting Complement Component 5, in Healthy Subjects and Patients with Paroxysmal Nocturnal Hemoglobinuria.
Badri P, Jiang X, Borodovsky A, Najafian N, Kim J, Clausen VA, Goel V, Habtemariam B, Robbie GJ. Badri P, et al. Among authors: habtemariam b. Clin Pharmacokinet. 2021 Mar;60(3):365-378. doi: 10.1007/s40262-020-00940-9. Clin Pharmacokinet. 2021. PMID: 33047216 Clinical Trial.
Phase 3 trial of lumasiran for primary hyperoxaluria type 1: A new RNAi therapeutic in infants and young children.
Sas DJ, Magen D, Hayes W, Shasha-Lavsky H, Michael M, Schulte I, Sellier-Leclerc AL, Lu J, Seddighzadeh A, Habtemariam B, McGregor TL, Fujita KP, Frishberg Y; ILLUMINATE-B Workgroup. Sas DJ, et al. Among authors: habtemariam b. Genet Med. 2021 Dec 7:S1098-3600(21)05376-4. doi: 10.1016/j.gim.2021.10.024. Online ahead of print. Genet Med. 2021. PMID: 34906487 Free article.
Population pharmacokinetics of valsartan in pediatrics.
Habtemariam B, Sallas W, Sunkara G, Kern S, Jarugula V, Pillai G. Habtemariam B, et al. Drug Metab Pharmacokinet. 2009;24(2):145-52. doi: 10.2133/dmpk.24.145. Drug Metab Pharmacokinet. 2009. PMID: 19430170 Free article.
FDA Approval: Belinostat for the Treatment of Patients with Relapsed or Refractory Peripheral T-cell Lymphoma.
Lee HZ, Kwitkowski VE, Del Valle PL, Ricci MS, Saber H, Habtemariam BA, Bullock J, Bloomquist E, Li Shen Y, Chen XH, Brown J, Mehrotra N, Dorff S, Charlab R, Kane RC, Kaminskas E, Justice R, Farrell AT, Pazdur R. Lee HZ, et al. Among authors: habtemariam ba. Clin Cancer Res. 2015 Jun 15;21(12):2666-70. doi: 10.1158/1078-0432.CCR-14-3119. Epub 2015 Mar 23. Clin Cancer Res. 2015. PMID: 25802282 Free article.
U.s. Food and Drug Administration approval: carfilzomib for the treatment of multiple myeloma.
Herndon TM, Deisseroth A, Kaminskas E, Kane RC, Koti KM, Rothmann MD, Habtemariam B, Bullock J, Bray JD, Hawes J, Palmby TR, Jee J, Adams W, Mahayni H, Brown J, Dorantes A, Sridhara R, Farrell AT, Pazdur R. Herndon TM, et al. Among authors: habtemariam b. Clin Cancer Res. 2013 Sep 1;19(17):4559-63. doi: 10.1158/1078-0432.CCR-13-0755. Epub 2013 Jun 17. Clin Cancer Res. 2013. PMID: 23775332 Free article.
17 results