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Year Number of Results
2019 1
2021 2
2022 2
2023 3
2024 0

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Page 1
CAR-T cells targeting IL-1RAP produced in a closed semiautomatic system are ready for the first phase I clinical investigation in humans.
Nicod C, da Rocha MN, Warda W, Roussel X, Haderbache R, Seffar E, Trad R, Bouquet L, Goncalves M, Bosdure L, Laude MC, Guiot M, Ferrand C, Deschamps M. Nicod C, et al. Among authors: haderbache r. Curr Res Transl Med. 2023 Apr-Jun;71(2):103385. doi: 10.1016/j.retram.2023.103385. Epub 2023 Feb 4. Curr Res Transl Med. 2023. PMID: 36773434 Free article.
Coated recombinant target protein helps explore IL-1RAP CAR T-cell functionality in vitro.
Da Rocha MN, Guiot M, Nicod C, Trad R, Bouquet L, Haderbache R, Warda W, Baurand PE, Jouanneau C, Dulieu P, Deschamps M, Ferrand C. Da Rocha MN, et al. Among authors: haderbache r. Immunol Res. 2023 Apr;71(2):276-282. doi: 10.1007/s12026-022-09348-y. Epub 2022 Dec 2. Immunol Res. 2023. PMID: 36456721 Free PMC article. No abstract available.
RapaCaspase-9-based suicide gene applied to the safety of IL-1RAP CAR-T cells.
Bouquet L, Bôle-Richard E, Warda W, Neto Da Rocha M, Trad R, Nicod C, Haderbache R, Genin D, Ferrand C, Deschamps M. Bouquet L, et al. Among authors: haderbache r. Gene Ther. 2023 Sep;30(9):706-713. doi: 10.1038/s41434-023-00404-2. Epub 2023 May 12. Gene Ther. 2023. PMID: 37173386 Free PMC article.
[IL-1RAP as a candidate for CAR T-cells immunotherapy].
Neto Da Rocha M, Trad R, Warda W, Haderbache R, Bouquet L, Nicod C, Deschamps M, Ferrand C. Neto Da Rocha M, et al. Among authors: haderbache r. Med Sci (Paris). 2019 Jun-Jul;35(6-7):497-500. doi: 10.1051/medsci/2019105. Epub 2019 Jul 5. Med Sci (Paris). 2019. PMID: 31274074 Free article. French. No abstract available.
Chimeric antigen receptor T-cells targeting IL-1RAP: a promising new cellular immunotherapy to treat acute myeloid leukemia.
Trad R, Warda W, Alcazer V, Neto da Rocha M, Berceanu A, Nicod C, Haderbache R, Roussel X, Desbrosses Y, Daguindau E, Renosi F, Roumier C, Bouquet L, Biichle S, Guiot M, Seffar E, Caillot D, Depil S, Robinet E, Salma Y, Deconinck E, Deschamps M, Ferrand C. Trad R, et al. Among authors: haderbache r. J Immunother Cancer. 2022 Jul;10(7):e004222. doi: 10.1136/jitc-2021-004222. J Immunother Cancer. 2022. PMID: 35803613 Free PMC article.
Overcoming target epitope masking resistance that can occur on low-antigen-expresser AML blasts after IL-1RAP chimeric antigen receptor T cell therapy using the inducible caspase 9 suicide gene safety switch.
Warda W, Da Rocha MN, Trad R, Haderbache R, Salma Y, Bouquet L, Roussel X, Nicod C, Deschamps M, Ferrand C. Warda W, et al. Among authors: haderbache r. Cancer Gene Ther. 2021 Dec;28(12):1365-1375. doi: 10.1038/s41417-020-00284-3. Epub 2021 Jan 7. Cancer Gene Ther. 2021. PMID: 33414517 Free PMC article.
Droplet digital PCR allows vector copy number assessment and monitoring of experimental CAR T cells in murine xenograft models or approved CD19 CAR T cell-treated patients.
Haderbache R, Warda W, Hervouet E, da Rocha MN, Trad R, Allain V, Nicod C, Thieblemeont C, Boissel N, Varlet P, Agha IY, Bouquet L, Guiot M, Venet F, Sujobert P, Roussel X, Rouzaire PO, Caillot D, Casasnovas O, Bories JC, Bachy E, Caillat-Zucman S, Deschamps M, Ferrand C. Haderbache R, et al. J Transl Med. 2021 Jun 21;19(1):265. doi: 10.1186/s12967-021-02925-z. J Transl Med. 2021. PMID: 34154602 Free PMC article.