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Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records.
Þorsteinsson H, Baukmann HA, Sveinsdóttir HS, Halldórsdóttir DÞ, Grzymala B, Hillman C, Rolfe-Tarrant J, Parker MO, Cope JL, Ravarani CNJ, Schmidt MF, Karlsson KÆ. Þorsteinsson H, et al. Among authors: halldorsdottir dth. Neuropsychopharmacology. 2025 Feb 14. doi: 10.1038/s41386-025-02062-x. Online ahead of print. Neuropsychopharmacology. 2025. PMID: 39953207
Metabolomic and lipidomic profiling reveals convergent pathways in attention deficit hyperactivity disorder therapeutics: Insights from established and emerging treatments.
Grzymala B, Þorsteinsson H, Halldórsdóttir DÞ, Sveinsdóttir HS, Sævarsdóttir BR, Norton WHJ, Parker MO, Rolfsson Ó, Karlsson KÆ. Grzymala B, et al. Among authors: halldorsdottir dth. J Pharmacol Exp Ther. 2025 Feb 21;392(4):103403. doi: 10.1016/j.jpet.2025.103403. Online ahead of print. J Pharmacol Exp Ther. 2025. PMID: 40081232 Free article.