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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
1993 1
1994 1
1995 2
1996 4
1998 2
1999 1
2000 2
2001 2
2002 2
2003 4
2004 5
2005 1
2006 5
2007 2
2008 5
2009 1
2010 6
2011 11
2012 5
2013 15
2014 9
2015 13
2016 8
2017 8
2018 4
2019 6
2020 11
2021 2
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121 results
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Page 1
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.
Sanij E, Hannan KM, Xuan J, Yan S, Ahern JE, Trigos AS, Brajanovski N, Son J, Chan KT, Kondrashova O, Lieschke E, Wakefield MJ, Frank D, Ellis S, Cullinane C, Kang J, Poortinga G, Nag P, Deans AJ, Khanna KK, Mileshkin L, McArthur GA, Soong J, Berns EMJJ, Hannan RD, Scott CL, Sheppard KE, Pearson RB. Sanij E, et al. Among authors: hannan rd. Nat Commun. 2020 May 26;11(1):2641. doi: 10.1038/s41467-020-16393-4. Nat Commun. 2020. PMID: 32457376 Free PMC article.
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35.
Liu PY, Tee AE, Milazzo G, Hannan KM, Maag J, Mondal S, Atmadibrata B, Bartonicek N, Peng H, Ho N, Mayoh C, Ciaccio R, Sun Y, Henderson MJ, Gao J, Everaert C, Hulme AJ, Wong M, Lan Q, Cheung BB, Shi L, Wang JY, Simon T, Fischer M, Zhang XD, Marshall GM, Norris MD, Haber M, Vandesompele J, Li J, Mestdagh P, Hannan RD, Dinger ME, Perini G, Liu T. Liu PY, et al. Among authors: hannan rd. Nat Commun. 2019 Nov 5;10(1):5026. doi: 10.1038/s41467-019-12971-3. Nat Commun. 2019. PMID: 31690716 Free PMC article.
Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.
Lawrence MG, Obinata D, Sandhu S, Selth LA, Wong SQ, Porter LH, Lister N, Pook D, Pezaro CJ, Goode DL, Rebello RJ, Clark AK, Papargiris M, Van Gramberg J, Hanson AR, Banks P, Wang H, Niranjan B, Keerthikumar S, Hedwards S, Huglo A, Yang R, Henzler C, Li Y, Lopez-Campos F, Castro E, Toivanen R, Azad A, Bolton D, Goad J, Grummet J, Harewood L, Kourambas J, Lawrentschuk N, Moon D, Murphy DG, Sengupta S, Snow R, Thorne H, Mitchell C, Pedersen J, Clouston D, Norden S, Ryan A, Dehm SM, Tilley WD, Pearson RB, Hannan RD, Frydenberg M, Furic L, Taylor RA, Risbridger GP. Lawrence MG, et al. Among authors: hannan rd. Eur Urol. 2018 Nov;74(5):562-572. doi: 10.1016/j.eururo.2018.06.020. Epub 2018 Jul 23. Eur Urol. 2018. PMID: 30049486 Free PMC article.
Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.
Drygin D, Lin A, Bliesath J, Ho CB, O'Brien SE, Proffitt C, Omori M, Haddach M, Schwaebe MK, Siddiqui-Jain A, Streiner N, Quin JE, Sanij E, Bywater MJ, Hannan RD, Ryckman D, Anderes K, Rice WG. Drygin D, et al. Among authors: hannan rd. Cancer Res. 2011 Feb 15;71(4):1418-30. doi: 10.1158/0008-5472.CAN-10-1728. Epub 2010 Dec 15. Cancer Res. 2011. PMID: 21159662 Free article.
Therapeutic Approaches Targeting MYC-Driven Prostate Cancer.
Rebello RJ, Pearson RB, Hannan RD, Furic L. Rebello RJ, et al. Among authors: hannan rd. Genes (Basel). 2017 Feb 16;8(2):71. doi: 10.3390/genes8020071. Genes (Basel). 2017. PMID: 28212321 Free PMC article. Review.
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.
Gao J, Jung M, Mayoh C, Venkat P, Hannan KM, Fletcher JI, Kamili A, Gifford AJ, Kusnadi EP, Pearson RB, Hannan RD, Haber M, Norris MD, Somers K, Henderson MJ. Gao J, et al. Among authors: hannan rd. Cancer Res. 2020 Sep 1;80(17):3706-3718. doi: 10.1158/0008-5472.CAN-19-3914. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651259
Cohesin mutations are synthetic lethal with stimulation of WNT signaling.
Chin CV, Antony J, Ketharnathan S, Labudina A, Gimenez G, Parsons KM, He J, George AJ, Pallotta MM, Musio A, Braithwaite A, Guilford P, Hannan RD, Horsfield JA. Chin CV, et al. Among authors: hannan rd. Elife. 2020 Dec 7;9:e61405. doi: 10.7554/eLife.61405. Elife. 2020. PMID: 33284104 Free PMC article.
Targeting the nucleolus for cancer intervention.
Quin JE, Devlin JR, Cameron D, Hannan KM, Pearson RB, Hannan RD. Quin JE, et al. Among authors: hannan rd. Biochim Biophys Acta. 2014 Jun;1842(6):802-16. doi: 10.1016/j.bbadis.2013.12.009. Epub 2014 Jan 2. Biochim Biophys Acta. 2014. PMID: 24389329 Free article. Review.
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