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1999 1
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Pharmacology of LY315920/S-5920, [[3-(aminooxoacetyl)-2-ethyl-1- (phenylmethyl)-1H-indol-4-yl]oxy] acetate, a potent and selective secretory phospholipase A2 inhibitor: A new class of anti-inflammatory drugs, SPI.
Snyder DW, Bach NJ, Dillard RD, Draheim SE, Carlson DG, Fox N, Roehm NW, Armstrong CT, Chang CH, Hartley LW, Johnson LM, Roman CR, Smith AC, Song M, Fleisch JH. Snyder DW, et al. Among authors: hartley lw. J Pharmacol Exp Ther. 1999 Mar;288(3):1117-24. J Pharmacol Exp Ther. 1999. PMID: 10027849
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides.
Dillard RD, Bach NJ, Draheim SE, Berry DR, Carlson DG, Chirgadze NY, Clawson DK, Hartley LW, Johnson LM, Jones ND, McKinney ER, Mihelich ED, Olkowski JL, Schevitz RW, Smith AC, Snyder DW, Sommers CD, Wery JP. Dillard RD, et al. Among authors: hartley lw. J Med Chem. 1996 Dec 20;39(26):5119-36. doi: 10.1021/jm960485v. J Med Chem. 1996. PMID: 9005255
Carbocyclic[g]indole inhibitors of human nonpancreatic s-PLA2.
Sawyer JS, Beight DW, Smith EC, Snyder DW, Chastain MK, Tielking RL, Hartley LW, Carlson DG. Sawyer JS, et al. Among authors: hartley lw. J Med Chem. 2005 Feb 10;48(3):893-6. doi: 10.1021/jm0401309. J Med Chem. 2005. PMID: 15689175
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides.
Draheim SE, Bach NJ, Dillard RD, Berry DR, Carlson DG, Chirgadze NY, Clawson DK, Hartley LW, Johnson LM, Jones ND, McKinney ER, Mihelich ED, Olkowski JL, Schevitz RW, Smith AC, Snyder DW, Sommers CD, Wery JP. Draheim SE, et al. Among authors: hartley lw. J Med Chem. 1996 Dec 20;39(26):5159-75. doi: 10.1021/jm960487f. J Med Chem. 1996. PMID: 8978844
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 2. Indole-3-acetamides with additional functionality.
Dillard RD, Bach NJ, Draheim SE, Berry DR, Carlson DG, Chirgadze NY, Clawson DK, Hartley LW, Johnson LM, Jones ND, McKinney ER, Mihelich ED, Olkowski JL, Schevitz RW, Smith AC, Snyder DW, Sommers CD, Wery JP. Dillard RD, et al. Among authors: hartley lw. J Med Chem. 1996 Dec 20;39(26):5137-58. doi: 10.1021/jm960486n. J Med Chem. 1996. PMID: 8978843