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Arterial retention of remnant lipoproteins ex vivo is increased in insulin resistance because of increased arterial biglycan and production of cholesterol-rich atherogenic particles that can be improved by ezetimibe in the JCR:LA-cp rat.
Mangat R, Warnakula S, Borthwick F, Hassanali Z, Uwiera RR, Russell JC, Cheeseman CI, Vine DF, Proctor SD. Mangat R, et al. Among authors: hassanali z. J Am Heart Assoc. 2012 Oct;1(5):e003434. doi: 10.1161/JAHA.112.003434. Epub 2012 Oct 25. J Am Heart Assoc. 2012. PMID: 23316299 Free PMC article.