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Epigenetic Control of a Local Chromatin Landscape.

Chiarella AM, Lu D, Hathaway NA. Chiarella AM, et al. Among authors: hathaway na. Int J Mol Sci. 2020 Jan 31;21(3):943. doi: 10.3390/ijms21030943. Int J Mol Sci. 2020. PMID: 32023873 Free PMC article. Review.

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LSH mediates gene repression through macroH2A deposition.

Ni K, Ren J, Xu X, He Y, Finney R, Braun SMG, Hathaway NA, Crabtree GR, Muegge K. Ni K, et al. Among authors: hathaway na. Nat Commun. 2020 Nov 6;11(1):5647. doi: 10.1038/s41467-020-19159-0. Nat Commun. 2020. PMID: 33159050 Free PMC article.

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Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding.

Skrajna A, Goldfarb D, Kedziora KM, Cousins EM, Grant GD, Spangler CJ, Barbour EH, Yan X, Hathaway NA, Brown NG, Cook JG, Major MB, McGinty RK. Skrajna A, et al. Among authors: hathaway na. Nucleic Acids Res. 2020 Sep 25;48(17):9415-9432. doi: 10.1093/nar/gkaa544. Nucleic Acids Res. 2020. PMID: 32658293 Free PMC article.

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Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome.

Chory EJ, Calarco JP, Hathaway NA, Bell O, Neel DS, Crabtree GR. Chory EJ, et al. Among authors: hathaway na. Mol Cell. 2019 Jan 3;73(1):61-72.e3. doi: 10.1016/j.molcel.2018.10.028. Epub 2018 Nov 21. Mol Cell. 2019. PMID: 30472189 Free PMC article.

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A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex.

Waybright JM, Clinkscales SE, Barnash KD, Budziszewski GR, Rectenwald JM, Chiarella AM, Norris-Drouin JL, Cholensky SH, Pearce KH, Herring LE, McGinty RK, Hathaway NA, James LI. Waybright JM, et al. Among authors: hathaway na. ACS Chem Biol. 2021 Sep 17;16(9):1721-1736. doi: 10.1021/acschembio.1c00429. Epub 2021 Aug 20. ACS Chem Biol. 2021. PMID: 34415726

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Epigenetic roots of immunologic disease and new methods for examining chromatin regulatory pathways.

MacDonald IA, Hathaway NA. MacDonald IA, et al. Among authors: hathaway na. Immunol Cell Biol. 2015 Mar;93(3):261-70. doi: 10.1038/icb.2014.105. Epub 2014 Dec 23. Immunol Cell Biol. 2015. PMID: 25533290 Review.

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Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma.

Gryder BE, Pomella S, Sayers C, Wu XS, Song Y, Chiarella AM, Bagchi S, Chou HC, Sinniah RS, Walton A, Wen X, Rota R, Hathaway NA, Zhao K, Chen J, Vakoc CR, Shern JF, Stanton BZ, Khan J. Gryder BE, et al. Among authors: hathaway na. Nat Genet. 2019 Dec;51(12):1714-1722. doi: 10.1038/s41588-019-0534-4. Epub 2019 Nov 29. Nat Genet. 2019. PMID: 31784732 Free PMC article.

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Pathway-Based High-Throughput Chemical Screen Identifies Compounds That Decouple Heterochromatin Transformations.

MacDonald IA, Butler KV, Herring LE, Clinkscales SE, Yelagandula R, Stecher K, Bell O, Graves LM, Jin J, Hathaway NA. MacDonald IA, et al. Among authors: hathaway na. SLAS Discov. 2019 Sep;24(8):802-816. doi: 10.1177/2472555219849838. Epub 2019 May 30. SLAS Discov. 2019. PMID: 31145866 Free PMC article.

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A simulation model of heterochromatin formation at submolecular detail.

Williams MR, Xiaokang Y, Hathaway NA, Kireev D. Williams MR, et al. Among authors: hathaway na. iScience. 2022 Jun 14;25(7):104590. doi: 10.1016/j.isci.2022.104590. eCollection 2022 Jul 15. iScience. 2022. PMID: 35800764 Free PMC article.

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Report and Application of a Tool Compound Data Set.

Butler KV, MacDonald IA, Hathaway NA, Jin J. Butler KV, et al. Among authors: hathaway na. J Chem Inf Model. 2017 Nov 27;57(11):2699-2706. doi: 10.1021/acs.jcim.7b00343. Epub 2017 Nov 2. J Chem Inf Model. 2017. PMID: 29035535 Free PMC article.

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