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Page 1
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium; de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Prentzell MT, et al. Among authors: heberle am. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. Cell. 2021. PMID: 33497611 Free PMC article.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: heberle am. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
The TSC Complex-mTORC1 Axis: From Lysosomes to Stress Granules and Back.
Rehbein U, Prentzell MT, Cadena Sandoval M, Heberle AM, Henske EP, Opitz CA, Thedieck K. Rehbein U, et al. Among authors: heberle am. Front Cell Dev Biol. 2021 Oct 29;9:751892. doi: 10.3389/fcell.2021.751892. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34778262 Free PMC article. Review.
Finding new edges: systems approaches to MTOR signaling.
Heberle AM, Rehbein U, Rodríguez Peiris M, Thedieck K. Heberle AM, et al. Biochem Soc Trans. 2021 Feb 26;49(1):41-54. doi: 10.1042/BST20190730. Biochem Soc Trans. 2021. PMID: 33544134 Free PMC article. Review.
Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity.
Abdellatif M, Trummer-Herbst V, Heberle AM, Humnig A, Pendl T, Durand S, Cerrato G, Hofer SJ, Islam M, Voglhuber J, Ramos Pittol JM, Kepp O, Hoefler G, Schmidt A, Rainer PP, Scherr D, von Lewinski D, Bisping E, McMullen JR, Diwan A, Eisenberg T, Madeo F, Thedieck K, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: heberle am. Circulation. 2022 Jun 21;145(25):1853-1866. doi: 10.1161/CIRCULATIONAHA.122.059863. Epub 2022 May 26. Circulation. 2022. PMID: 35616058 Free PMC article.
Molecular mechanisms of mTOR regulation by stress.
Heberle AM, Prentzell MT, van Eunen K, Bakker BM, Grellscheid SN, Thedieck K. Heberle AM, et al. Mol Cell Oncol. 2014 Dec 3;2(2):e970489. doi: 10.4161/23723548.2014.970489. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2014. PMID: 27308421 Free PMC article. Review.
mTORC1 Crosstalk With Stress Granules in Aging and Age-Related Diseases.
Cadena Sandoval M, Heberle AM, Rehbein U, Barile C, Ramos Pittol JM, Thedieck K. Cadena Sandoval M, et al. Among authors: heberle am. Front Aging. 2021 Oct 13;2:761333. doi: 10.3389/fragi.2021.761333. eCollection 2021. Front Aging. 2021. PMID: 35822040 Free PMC article. Review.
Comparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics.
Zhang Y, Dreyer B, Govorukhina N, Heberle AM, Končarević S, Krisp C, Opitz CA, Pfänder P, Bischoff R, Schlüter H, Kwiatkowski M, Thedieck K, Horvatovich PL. Zhang Y, et al. Among authors: heberle am. Anal Chem. 2022 Aug 9;94(31):10893-10906. doi: 10.1021/acs.analchem.2c01036. Epub 2022 Jul 26. Anal Chem. 2022. PMID: 35880733 Free PMC article.
Cardiac PI3K p110α attenuation delays aging and extends lifespan.
Abdellatif M, Eisenberg T, Heberle AM, Thedieck K, Kroemer G, Sedej S. Abdellatif M, et al. Among authors: heberle am. Cell Stress. 2022 Aug 8;6(8):72-75. doi: 10.15698/cst2022.08.270. eCollection 2022 Aug. Cell Stress. 2022. PMID: 36447531 Free PMC article.
Phosphoproteomics Profiling Defines a Target Landscape of the Basophilic Protein Kinases AKT, S6K, and RSK in Skeletal Myotubes.
Fricke AL, Mühlhäuser WWD, Reimann L, Zimmermann JP, Reichenbach C, Knapp B, Peikert CD, Heberle AM, Faessler E, Schäuble S, Hahn U, Thedieck K, Radziwill G, Warscheid B. Fricke AL, et al. Among authors: heberle am. J Proteome Res. 2023 Mar 3;22(3):768-789. doi: 10.1021/acs.jproteome.2c00505. Epub 2023 Feb 10. J Proteome Res. 2023. PMID: 36763541
16 results