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IMM-BCP-01, a patient-derived anti-SARS-CoV-2 antibody cocktail, is active across variants of concern including Omicron BA.1 and BA.2.
Nikitin PA, DiMuzio JM, Dowling JP, Patel NB, Bingaman-Steele JL, Heimbach BC, Henriquez N, Nicolescu C, Polley A, Sikorski EL, Howanski RJ, Nath M, Shukla H, Scheaffer SM, Finn JP, Liang LF, Smith T, Storm N, McKay LGA, Johnson RI, Malsick LE, Honko AN, Griffiths A, Diamond MS, Sarma P, Geising DH, Morin MJ, Robinson MK. Nikitin PA, et al. Among authors: heimbach bc. Sci Immunol. 2022 Sep 9;7(75):eabl9943. doi: 10.1126/sciimmunol.abl9943. Epub 2022 Sep 9. Sci Immunol. 2022. PMID: 35771946 Free PMC article.
Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein.
DiMuzio JM, Heimbach BC, Howanski RJ, Dowling JP, Patel NB, Henriquez N, Nicolescu C, Nath M, Polley A, Bingaman JL, Smith T, Harman BC, Robinson MK, Morin MJ, Nikitin PA. DiMuzio JM, et al. Among authors: heimbach bc. Vaccine X. 2021 Aug;8:100098. doi: 10.1016/j.jvacx.2021.100098. Epub 2021 Apr 24. Vaccine X. 2021. PMID: 33937741 Free PMC article.