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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1990 2
1991 4
1992 4
1993 11
1994 6
1995 6
1996 2
1997 9
1998 9
1999 4
2000 9
2001 5
2002 7
2003 8
2004 14
2005 10
2006 5
2007 10
2008 11
2009 10
2010 14
2011 10
2012 8
2013 19
2014 16
2015 10
2016 13
2017 6
2018 9
2019 15
2020 7
2021 9
2022 3
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275 results
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Page 1
PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN.
Pastore F, Bhagwat N, Pastore A, Radzisheuskaya A, Karzai A, Krishnan A, Li B, Bowman RL, Xiao W, Viny AD, Zouak A, Park YC, Cordner KB, Braunstein S, Maag JL, Grego A, Mehta J, Wang M, Lin H, Durham BH, Koche RP, Rampal RK, Helin K, Scherle P, Vaddi K, Levine RL. Pastore F, et al. Among authors: helin k. Cancer Discov. 2020 Nov;10(11):1742-1757. doi: 10.1158/2159-8290.CD-20-0026. Epub 2020 Jul 15. Cancer Discov. 2020. PMID: 32669286 Free PMC article.
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas.
Mohammad F, Weissmann S, Leblanc B, Pandey DP, Højfeldt JW, Comet I, Zheng C, Johansen JV, Rapin N, Porse BT, Tvardovskiy A, Jensen ON, Olaciregui NG, Lavarino C, Suñol M, de Torres C, Mora J, Carcaboso AM, Helin K. Mohammad F, et al. Among authors: helin k. Nat Med. 2017 Apr;23(4):483-492. doi: 10.1038/nm.4293. Epub 2017 Feb 27. Nat Med. 2017. PMID: 28263309
Oncohistones: drivers of pediatric cancers.
Mohammad F, Helin K. Mohammad F, et al. Among authors: helin k. Genes Dev. 2017 Dec 1;31(23-24):2313-2324. doi: 10.1101/gad.309013.117. Genes Dev. 2017. PMID: 29352018 Free PMC article. Review.
Inhibitors of histone demethylases.
Lohse B, Kristensen JL, Kristensen LH, Agger K, Helin K, Gajhede M, Clausen RP. Lohse B, et al. Among authors: helin k. Bioorg Med Chem. 2011 Jun 15;19(12):3625-36. doi: 10.1016/j.bmc.2011.01.046. Epub 2011 Feb 1. Bioorg Med Chem. 2011. PMID: 21596573 Review.
Histone methyltransferases in cancer.
Albert M, Helin K. Albert M, et al. Among authors: helin k. Semin Cell Dev Biol. 2010 Apr;21(2):209-20. doi: 10.1016/j.semcdb.2009.10.007. Epub 2009 Nov 3. Semin Cell Dev Biol. 2010. PMID: 19892027 Review.
Profiling cancer.
Ciro M, Bracken AP, Helin K. Ciro M, et al. Among authors: helin k. Curr Opin Cell Biol. 2003 Apr;15(2):213-20. doi: 10.1016/s0955-0674(03)00007-3. Curr Opin Cell Biol. 2003. PMID: 12648678 Review.
275 results