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Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.
Gao Y, Cai C, Wullimann D, Niessl J, Rivera-Ballesteros O, Chen P, Lange J, Cuapio A, Blennow O, Hansson L, Mielke S, Nowak P, Vesterbacka J, Akber M, Perez-Potti A, Sekine T, Müller TR, Boulouis C, Kammann T, Parrot T, Muvva JR, Sobkowiak M, Healy K, Bogdanovic G, Muschiol S, Söderdahl G, Österborg A, Hellgren F, Grifoni A, Weiskopf D, Sette A, Loré K, Sällberg Chen M, Ljungman P, Sandberg JK, Smith CIE, Bergman P, Ljunggren HG, Aleman S, Buggert M. Gao Y, et al. Among authors: hellgren f. Immunity. 2022 Sep 13;55(9):1732-1746.e5. doi: 10.1016/j.immuni.2022.07.005. Epub 2022 Jul 19. Immunity. 2022. PMID: 35961317 Free PMC article.
NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals.
Cuapio A, Boulouis C, Filipovic I, Wullimann D, Kammann T, Parrot T, Chen P, Akber M, Gao Y, Hammer Q, Strunz B, Pérez Potti A, Rivera Ballesteros O, Lange J, Muvva JR, Bergman P, Blennow O, Hansson L, Mielke S, Nowak P, Söderdahl G, Österborg A, Smith CIE, Bogdanovic G, Muschiol S, Hellgren F, Loré K, Sobkowiak MJ, Gabarrini G, Healy K, Sällberg Chen M, Alici E, Björkström NK, Buggert M, Ljungman P, Sandberg JK, Aleman S, Ljunggren HG. Cuapio A, et al. Among authors: hellgren f. Mol Med. 2022 Feb 8;28(1):20. doi: 10.1186/s10020-022-00443-2. Mol Med. 2022. PMID: 35135470 Free PMC article.
A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses.
Lenart K, Hellgren F, Ols S, Yan X, Cagigi A, Cerveira RA, Winge I, Hanczak J, Mueller SO, Jasny E, Schwendt K, Rauch S, Petsch B, Loré K. Lenart K, et al. Among authors: hellgren f. Mol Ther Methods Clin Dev. 2022 Dec 8;27:309-323. doi: 10.1016/j.omtm.2022.10.001. Epub 2022 Oct 6. Mol Ther Methods Clin Dev. 2022. PMID: 36217434 Free PMC article.
Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity.
Falck-Jones S, Vangeti S, Yu M, Falck-Jones R, Cagigi A, Badolati I, Österberg B, Lautenbach MJ, Åhlberg E, Lin A, Lepzien R, Szurgot I, Lenart K, Hellgren F, Maecker H, Sälde J, Albert J, Johansson N, Bell M, Loré K, Färnert A, Smed-Sörensen A. Falck-Jones S, et al. Among authors: hellgren f. J Clin Invest. 2021 Mar 15;131(6):e144734. doi: 10.1172/JCI144734. J Clin Invest. 2021. PMID: 33492309 Free PMC article.
Corrigendum: Induction of Robust B Cell Responses After Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.
Lindgren G, Ols S, Liang F, Thompson EA, Lin A, Hellgren F, Bahl K, John S, Yuzhakov O, Hassett KJ, Brito LA, Salter H, Ciaramella G, Loré K. Lindgren G, et al. Among authors: hellgren f. Front Immunol. 2019 Apr 2;10:614. doi: 10.3389/fimmu.2019.00614. eCollection 2019. Front Immunol. 2019. PMID: 31001251 Free PMC article.
Deficits in the IgG+ memory B-cell recovery after anthracycline treatment is confined to the spleen of rhesus macaques.
Lasaviciute G, Bricaud AL, Hellgren F, Ingelman-Sundberg HM, Eksborg S, Jonker M, Haanstra KG, Hed Myrberg I, Sverremark-Ekström E, Loré K, Saghafian-Hedengren S, Nilsson A. Lasaviciute G, et al. Among authors: hellgren f. Clin Transl Immunology. 2020 Jul 2;9(7):e1150. doi: 10.1002/cti2.1150. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32642064 Free PMC article.
Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.
Lindgren G, Ols S, Liang F, Thompson EA, Lin A, Hellgren F, Bahl K, John S, Yuzhakov O, Hassett KJ, Brito LA, Salter H, Ciaramella G, Loré K. Lindgren G, et al. Among authors: hellgren f. Front Immunol. 2017 Nov 13;8:1539. doi: 10.3389/fimmu.2017.01539. eCollection 2017. Front Immunol. 2017. PMID: 29181005 Free PMC article.