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Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing.
Adler BA, Hessler T, Cress BF, Lahiri A, Mutalik VK, Barrangou R, Banfield J, Doudna JA. Adler BA, et al. Among authors: hessler t. Nat Microbiol. 2022 Dec;7(12):1967-1979. doi: 10.1038/s41564-022-01258-x. Epub 2022 Oct 31. Nat Microbiol. 2022. PMID: 36316451 Free PMC article.
Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini I, Emmenegger L, Zappulo A, Rybak-Wolf A, Wurmus R, Martinez AO, Jara CC, Boltengagen A, Hessler T, Mastrobuoni G, Kempa S, Zinzen R, Woehler A, Rajewsky N. Legnini I, et al. Among authors: hessler t. Nat Methods. 2023 Sep 21. doi: 10.1038/s41592-023-01986-w. Online ahead of print. Nat Methods. 2023. PMID: 37735569