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Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing.
Adler BA, Hessler T, Cress BF, Lahiri A, Mutalik VK, Barrangou R, Banfield J, Doudna JA. Adler BA, et al. Among authors: hessler t. Nat Microbiol. 2022 Dec;7(12):1967-1979. doi: 10.1038/s41564-022-01258-x. Epub 2022 Oct 31. Nat Microbiol. 2022. PMID: 36316451 Free PMC article.
Spatiotemporal, optogenetic control of gene expression in organoids.
Legnini I, Emmenegger L, Zappulo A, Rybak-Wolf A, Wurmus R, Martinez AO, Jara CC, Boltengagen A, Hessler T, Mastrobuoni G, Kempa S, Zinzen R, Woehler A, Rajewsky N. Legnini I, et al. Among authors: hessler t. Nat Methods. 2023 Oct;20(10):1544-1552. doi: 10.1038/s41592-023-01986-w. Epub 2023 Sep 21. Nat Methods. 2023. PMID: 37735569 Free PMC article.
CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.
Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, Tsuchida CA, Tran RV, Hofman L, Shi H, Wasko KM, Zhou Z, Xia C, Al-Shimary MJ, Patel JR, Thomas VCJX, Pattali R, Kan MJ, Vardapetyan A, Yang A, Lahiri A, Maxwell MF, Murdock AG, Ramit GC, Henderson HR, Calvert RW, Bamert RS, Knott GJ, Lapinaite A, Pausch P, Cofsky JC, Sontheimer EJ, Wiedenheft B, Fineran PC, Brouns SJJ, Sashital DG, Thomas BC, Brown CT, Goltsman DSA, Barrangou R, Siksnys V, Banfield JF, Savage DF, Doudna JA. Adler BA, et al. Among authors: hessler t. Nucleic Acids Res. 2023 Oct 27:gkad890. doi: 10.1093/nar/gkad890. Online ahead of print. Nucleic Acids Res. 2023. PMID: 37889041
11 results