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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1995 2
1996 2
1997 1
1998 1
1999 1
2000 1
2004 3
2005 1
2006 2
2007 1
2014 1
2016 1
2018 2
2021 0
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20 results
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Page 1
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer.
Berns K, Horlings HM, Hennessy BT, Madiredjo M, Hijmans EM, Beelen K, Linn SC, Gonzalez-Angulo AM, Stemke-Hale K, Hauptmann M, Beijersbergen RL, Mills GB, van de Vijver MJ, Bernards R. Berns K, et al. Among authors: hijmans em. Cancer Cell. 2007 Oct;12(4):395-402. doi: 10.1016/j.ccr.2007.08.030. Cancer Cell. 2007. PMID: 17936563 Free article. Clinical Trial.
ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors.
Berns K, Caumanns JJ, Hijmans EM, Gennissen AMC, Severson TM, Evers B, Wisman GBA, Jan Meersma G, Lieftink C, Beijersbergen RL, Itamochi H, van der Zee AGJ, de Jong S, Bernards R. Berns K, et al. Among authors: hijmans em. Oncogene. 2018 Aug;37(33):4611-4625. doi: 10.1038/s41388-018-0300-6. Epub 2018 May 15. Oncogene. 2018. PMID: 29760405 Free PMC article.
Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
Caumanns JJ, Berns K, Wisman GBA, Fehrmann RSN, Tomar T, Klip H, Meersma GJ, Hijmans EM, Gennissen AMC, Duiker EW, Weening D, Itamochi H, Kluin RJC, Reyners AKL, Birrer MJ, Salvesen HB, Vergote I, van Nieuwenhuysen E, Brenton J, Braicu EI, Kupryjanczyk J, Spiewankiewicz B, Mittempergher L, Bernards R, van der Zee AGJ, de Jong S. Caumanns JJ, et al. Among authors: hijmans em. Clin Cancer Res. 2018 Aug 15;24(16):3928-3940. doi: 10.1158/1078-0432.CCR-17-3060. Epub 2018 Apr 23. Clin Cancer Res. 2018. PMID: 29685880 Free PMC article.
USP9X downregulation renders breast cancer cells resistant to tamoxifen.
Oosterkamp HM, Hijmans EM, Brummelkamp TR, Canisius S, Wessels LF, Zwart W, Bernards R. Oosterkamp HM, et al. Among authors: hijmans em. Cancer Res. 2014 Jul 15;74(14):3810-20. doi: 10.1158/0008-5472.CAN-13-1960. Cancer Res. 2014. PMID: 25028367 Free article.
Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.
Berns K, Sonnenblick A, Gennissen A, Brohée S, Hijmans EM, Evers B, Fumagalli D, Desmedt C, Loibl S, Denkert C, Neven P, Guo W, Zhang F, Knijnenburg TA, Bosse T, van der Heijden MS, Hindriksen S, Nijkamp W, Wessels LF, Joensuu H, Mills GB, Beijersbergen RL, Sotiriou C, Bernards R. Berns K, et al. Among authors: hijmans em. Clin Cancer Res. 2016 Nov 1;22(21):5238-5248. doi: 10.1158/1078-0432.CCR-15-2996. Epub 2016 May 12. Clin Cancer Res. 2016. PMID: 27172896 Free article.
Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.
Brummelkamp TR, Berns K, Hijmans EM, Mullenders J, Fabius A, Heimerikx M, Velds A, Kerkhoven RM, Madiredjo M, Bernards R, Beijersbergen RL. Brummelkamp TR, et al. Among authors: hijmans em. Cold Spring Harb Symp Quant Biol. 2004;69:439-45. doi: 10.1101/sqb.2004.69.439. Cold Spring Harb Symp Quant Biol. 2004. PMID: 16117679 No abstract available.
A functionally distinct member of the DP family of E2F subunits.
Milton A, Luoto K, Ingram L, Munro S, Logan N, Graham AL, Brummelkamp TR, Hijmans EM, Bernards R, La Thangue NB. Milton A, et al. Among authors: hijmans em. Oncogene. 2006 May 25;25(22):3212-8. doi: 10.1038/sj.onc.1209343. Oncogene. 2006. PMID: 16418725
Functional analysis of Burkitt's lymphoma mutant c-Myc proteins.
Smith-Sørensen B, Hijmans EM, Beijersbergen RL, Bernards R. Smith-Sørensen B, et al. Among authors: hijmans em. J Biol Chem. 1996 Mar 8;271(10):5513-8. doi: 10.1074/jbc.271.10.5513. J Biol Chem. 1996. PMID: 8621409 Free article.
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: hijmans em. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
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