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Year Number of Results
2019 2
2020 3
2021 1
2023 3
2024 1

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10 results

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Page 1
Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute.
Wang B, Wang M, Zhang W, Xiao T, Chen CH, Wu A, Wu F, Traugh N, Wang X, Li Z, Mei S, Cui Y, Shi S, Lipp JJ, Hinterndorfer M, Zuber J, Brown M, Li W, Liu XS. Wang B, et al. Among authors: hinterndorfer m. Nat Protoc. 2019 Mar;14(3):756-780. doi: 10.1038/s41596-018-0113-7. Epub 2019 Feb 1. Nat Protoc. 2019. PMID: 30710114 Free PMC article.
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida M, Hinterndorfer M, Brunner H, Grishkovskaya I, Singh K, Schleiffer A, Jude J, Deswal S, Kalis R, Vunjak M, Lendl T, Imre R, Roitinger E, Neumann T, Kandolf S, Schutzbier M, Mechtler K, Versteeg GA, Haselbach D, Zuber J. de Almeida M, et al. Among authors: hinterndorfer m. Nature. 2021 Nov;599(7885):491-496. doi: 10.1038/s41586-021-04035-8. Epub 2021 Oct 28. Nature. 2021. PMID: 34711951
Targeted protein degradation via intramolecular bivalent glues.
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schätz C, Rukavina A, Husnjak K, Wegner M, Correa-Sáez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A. Hsia O, et al. Among authors: hinterndorfer m. Nature. 2024 Feb 21. doi: 10.1038/s41586-024-07089-6. Online ahead of print. Nature. 2024. PMID: 38383787
SPOP targets the immune transcription factor IRF1 for proteasomal degradation.
Schwartz I, Vunjak M, Budroni V, Cantoran García A, Mastrovito M, Soderholm A, Hinterndorfer M, de Almeida M, Hacker K, Wang J, Froussios K, Jude J, Decker T, Zuber J, Versteeg GA. Schwartz I, et al. Among authors: hinterndorfer m. Elife. 2023 Aug 25;12:e89951. doi: 10.7554/eLife.89951. Elife. 2023. PMID: 37622993 Free PMC article.
Precision RNAi using synthetic shRNAmir target sites.
Hoffmann T, Hörmann A, Corcokovic M, Zmajkovic J, Hinterndorfer M, Salkanovic J, Spreitzer F, Köferle A, Gitschtaler K, Popa A, Oberndorfer S, Andersch F, Schaefer M, Fellner M, Budano N, Ruppert JG, Chetta P, Wurm M, Zuber J, Neumüller RA. Hoffmann T, et al. Among authors: hinterndorfer m. Elife. 2023 Aug 8;12:RP84792. doi: 10.7554/eLife.84792. Elife. 2023. PMID: 37552050 Free PMC article.
Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype.
Xue G, Xie J, Hinterndorfer M, Cigler M, Dötsch L, Imrichova H, Lampe P, Cheng X, Adariani SR, Winter GE, Waldmann H. Xue G, et al. Among authors: hinterndorfer m. Nat Commun. 2023 Nov 30;14(1):7908. doi: 10.1038/s41467-023-43657-6. Nat Commun. 2023. PMID: 38036533 Free PMC article.
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.
Michlits G, Jude J, Hinterndorfer M, de Almeida M, Vainorius G, Hubmann M, Neumann T, Schleiffer A, Burkard TR, Fellner M, Gijsbertsen M, Traunbauer A, Zuber J, Elling U. Michlits G, et al. Among authors: hinterndorfer m. Nat Methods. 2020 Jul;17(7):708-716. doi: 10.1038/s41592-020-0850-8. Epub 2020 Jun 8. Nat Methods. 2020. PMID: 32514112
STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
van der Lelij P, Newman JA, Lieb S, Jude J, Katis V, Hoffmann T, Hinterndorfer M, Bader G, Kraut N, Pearson MA, Peters JM, Zuber J, Gileadi O, Petronczki M. van der Lelij P, et al. Among authors: hinterndorfer m. Life Sci Alliance. 2020 May 28;3(7):e202000725. doi: 10.26508/lsa.202000725. Print 2020 Jul. Life Sci Alliance. 2020. PMID: 32467316 Free PMC article.
Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis.
Schlager S, Salomon C, Olt S, Albrecht C, Ebert A, Bergner O, Wachter J, Trapani F, Gerlach D, Voss T, Traunbauer A, Jude J, Hinterndorfer M, Minnich M, Schweifer N, Blake SM, Zinzalla V, Drobits B, McConnell DB, Kraut N, Pearson M, Zuber J, Koegl M. Schlager S, et al. Among authors: hinterndorfer m. Oncotarget. 2020 Mar 3;11(9):875-890. doi: 10.18632/oncotarget.27506. eCollection 2020 Mar 3. Oncotarget. 2020. PMID: 32180900 Free PMC article.