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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1955 1
1957 1
1958 1
1959 1
1960 1
1962 1
1963 1
1964 1
1965 2
1966 4
1967 4
1968 5
1969 10
1970 3
1971 8
1972 3
1973 4
1974 8
1975 7
1976 8
1977 8
1978 4
1979 10
1980 16
1981 13
1982 9
1983 17
1984 8
1985 21
1986 23
1987 18
1988 8
1989 19
1990 12
1991 21
1992 21
1993 16
1994 27
1995 20
1996 26
1997 33
1998 26
1999 34
2000 39
2001 36
2002 33
2003 49
2004 74
2005 50
2006 50
2007 65
2008 58
2009 54
2010 52
2011 69
2012 81
2013 70
2014 65
2015 83
2016 76
2017 99
2018 104
2019 89
2020 115
2021 55
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Article type
Publication date

Search Results

1,776 results
Results by year
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Page 1
Engineered CRISPR-Cas9 nuclease with expanded targeting space.
Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Nishimasu H, et al. Among authors: hirano s. Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. Science. 2018. PMID: 30166441 Free PMC article.
Adjuvant chemotherapy of S-1 versus gemcitabine for resected pancreatic cancer: a phase 3, open-label, randomised, non-inferiority trial (JASPAC 01).
Uesaka K, Boku N, Fukutomi A, Okamura Y, Konishi M, Matsumoto I, Kaneoka Y, Shimizu Y, Nakamori S, Sakamoto H, Morinaga S, Kainuma O, Imai K, Sata N, Hishinuma S, Ojima H, Yamaguchi R, Hirano S, Sudo T, Ohashi Y; JASPAC 01 Study Group. Uesaka K, et al. Among authors: hirano s. Lancet. 2016 Jul 16;388(10041):248-57. doi: 10.1016/S0140-6736(16)30583-9. Epub 2016 Jun 2. Lancet. 2016. PMID: 27265347 Clinical Trial.
Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations.
Wardell CP, Fujita M, Yamada T, Simbolo M, Fassan M, Karlic R, Polak P, Kim J, Hatanaka Y, Maejima K, Lawlor RT, Nakanishi Y, Mitsuhashi T, Fujimoto A, Furuta M, Ruzzenente A, Conci S, Oosawa A, Sasaki-Oku A, Nakano K, Tanaka H, Yamamoto Y, Michiaki K, Kawakami Y, Aikata H, Ueno M, Hayami S, Gotoh K, Ariizumi SI, Yamamoto M, Yamaue H, Chayama K, Miyano S, Getz G, Scarpa A, Hirano S, Nakamura T, Nakagawa H. Wardell CP, et al. Among authors: hirano s. J Hepatol. 2018 May;68(5):959-969. doi: 10.1016/j.jhep.2018.01.009. Epub 2018 Jan 31. J Hepatol. 2018. PMID: 29360550 Free article.
Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.
Fujimoto A, Furuta M, Totoki Y, Tsunoda T, Kato M, Shiraishi Y, Tanaka H, Taniguchi H, Kawakami Y, Ueno M, Gotoh K, Ariizumi S, Wardell CP, Hayami S, Nakamura T, Aikata H, Arihiro K, Boroevich KA, Abe T, Nakano K, Maejima K, Sasaki-Oku A, Ohsawa A, Shibuya T, Nakamura H, Hama N, Hosoda F, Arai Y, Ohashi S, Urushidate T, Nagae G, Yamamoto S, Ueda H, Tatsuno K, Ojima H, Hiraoka N, Okusaka T, Kubo M, Marubashi S, Yamada T, Hirano S, Yamamoto M, Ohdan H, Shimada K, Ishikawa O, Yamaue H, Chayama K, Miyano S, Aburatani H, Shibata T, Nakagawa H. Fujimoto A, et al. Among authors: hirano s. Nat Genet. 2016 May;48(5):500-9. doi: 10.1038/ng.3547. Epub 2016 Apr 11. Nat Genet. 2016. PMID: 27064257
ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer.
Hashimoto S, Furukawa S, Hashimoto A, Tsutaho A, Fukao A, Sakamura Y, Parajuli G, Onodera Y, Otsuka Y, Handa H, Oikawa T, Hata S, Nishikawa Y, Mizukami Y, Kodama Y, Murakami M, Fujiwara T, Hirano S, Sabe H. Hashimoto S, et al. Among authors: hirano s. Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17450-17459. doi: 10.1073/pnas.1901765116. Epub 2019 Aug 9. Proc Natl Acad Sci U S A. 2019. PMID: 31399545 Free PMC article.
Safety and efficacy of PD-1/PD-L1 blockade in patients with preexisting antinuclear antibodies.
Sakakida T, Ishikawa T, Chihara Y, Harita S, Uchino J, Tabuchi Y, Komori S, Asai J, Narukawa T, Arai A, Tsunezuka H, Kosuga T, Konishi H, Moriguchi M, Yasuda H, Hongo F, Inoue M, Hirano S, Ukimura O, Itoh Y, Taguchi T, Takayama K. Sakakida T, et al. Among authors: hirano s. Clin Transl Oncol. 2020 Jun;22(6):919-927. doi: 10.1007/s12094-019-02214-8. Epub 2019 Oct 1. Clin Transl Oncol. 2020. PMID: 31576495
Artery-first approach for pancreaticoduodenectomy.
Kawai M, Hirano S, Yamaue H. Kawai M, et al. Among authors: hirano s. J Hepatobiliary Pancreat Sci. 2018 Jun;25(6):319-320. doi: 10.1002/jhbp.554. J Hepatobiliary Pancreat Sci. 2018. PMID: 29665296 Review. No abstract available.
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