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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2007 2
2008 2
2012 3
2013 3
2014 5
2015 8
2016 3
2017 13
2018 9
2019 17
2020 18
2021 20
2022 19
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112 results
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Page 1
Towards the sustainable discovery and development of new antibiotics.
Miethke M, Pieroni M, Weber T, Brönstrup M, Hammann P, Halby L, Arimondo PB, Glaser P, Aigle B, Bode HB, Moreira R, Li Y, Luzhetskyy A, Medema MH, Pernodet JL, Stadler M, Tormo JR, Genilloud O, Truman AW, Weissman KJ, Takano E, Sabatini S, Stegmann E, Brötz-Oesterhelt H, Wohlleben W, Seemann M, Empting M, Hirsch AKH, Loretz B, Lehr CM, Titz A, Herrmann J, Jaeger T, Alt S, Hesterkamp T, Winterhalter M, Schiefer A, Pfarr K, Hoerauf A, Graz H, Graz M, Lindvall M, Ramurthy S, Karlén A, van Dongen M, Petkovic H, Keller A, Peyrane F, Donadio S, Fraisse L, Piddock LJV, Gilbert IH, Moser HE, Müller R. Miethke M, et al. Among authors: hirsch akh. Nat Rev Chem. 2021;5(10):726-749. doi: 10.1038/s41570-021-00313-1. Epub 2021 Aug 19. Nat Rev Chem. 2021. PMID: 34426795 Free PMC article. Review.
Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.
Chen F, Elgaher WAM, Winterhoff M, Büssow K, Waqas FH, Graner E, Pires-Afonso Y, Casares Perez L, de la Vega L, Sahini N, Czichon L, Zobl W, Zillinger T, Shehata M, Pleschka S, Bähre H, Falk C, Michelucci A, Schuchardt S, Blankenfeldt W, Hirsch AKH, Pessler F. Chen F, et al. Among authors: hirsch akh. Nat Metab. 2022 May;4(5):534-546. doi: 10.1038/s42255-022-00577-x. Epub 2022 Jun 2. Nat Metab. 2022. PMID: 35655026 Free PMC article.
François Diederich - In Memoriam*.
Hof F, Hirsch AKH. Hof F, et al. Among authors: hirsch akh. ChemMedChem. 2021 Jan 8;16(1):11-13. doi: 10.1002/cmdc.202000920. Epub 2020 Dec 14. ChemMedChem. 2021. PMID: 33314781
Saccharide-Containing Dynamic Proteoids.
Liu Y, Stuart MCA, Witte MD, Buhler E, Hirsch AKH. Liu Y, et al. Among authors: hirsch akh. Chemistry. 2017 Nov 16;23(64):16162-16166. doi: 10.1002/chem.201703584. Epub 2017 Oct 25. Chemistry. 2017. PMID: 28981987 Free PMC article.
Designed Spiroketal Protein Modulation.
Scheepstra M, Andrei SA, Unver MY, Hirsch AKH, Leysen S, Ottmann C, Brunsveld L, Milroy LG. Scheepstra M, et al. Among authors: hirsch akh. Angew Chem Int Ed Engl. 2017 May 8;56(20):5480-5484. doi: 10.1002/anie.201612504. Epub 2017 Apr 13. Angew Chem Int Ed Engl. 2017. PMID: 28407400 Free PMC article.
Druggability of the enzymes of the non-mevalonate-pathway.
Masini T, Kroezen BS, Hirsch AK. Masini T, et al. Among authors: hirsch ak. Drug Discov Today. 2013 Dec;18(23-24):1256-62. doi: 10.1016/j.drudis.2013.07.003. Epub 2013 Jul 13. Drug Discov Today. 2013. PMID: 23856326 Review.
Lipid-DNAs as Solubilizers of mTHPC.
Liu Y, de Vries JW, Liu Q, Hartman AM, Wieland GD, Wieczorek S, Börner HG, Wiehe A, Buhler E, Stuart MCA, Browne WR, Herrmann A, Hirsch AKH. Liu Y, et al. Among authors: hirsch akh. Chemistry. 2018 Jan 19;24(4):798-802. doi: 10.1002/chem.201705206. Epub 2017 Dec 18. Chemistry. 2018. PMID: 29194834 Free PMC article.
Concepts and Core Principles of Fragment-Based Drug Design.
Kirsch P, Hartman AM, Hirsch AKH, Empting M. Kirsch P, et al. Among authors: hirsch akh. Molecules. 2019 Nov 26;24(23):4309. doi: 10.3390/molecules24234309. Molecules. 2019. PMID: 31779114 Free PMC article. Review.
112 results