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Page 1
Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity.
Larsen MD, de Graaf EL, Sonneveld ME, Plomp HR, Nouta J, Hoepel W, Chen HJ, Linty F, Visser R, Brinkhaus M, Šuštić T, de Taeye SW, Bentlage AEH, Toivonen S, Koeleman CAM, Sainio S, Kootstra NA, Brouwer PJM, Geyer CE, Derksen NIL, Wolbink G, de Winther M, Sanders RW, van Gils MJ, de Bruin S, Vlaar APJ; Amsterdam UMC COVID-19; biobank study group; Rispens T, den Dunnen J, Zaaijer HL, Wuhrer M, Ellen van der Schoot C, Vidarsson G. Larsen MD, et al. Among authors: hoepel w. Science. 2021 Feb 26;371(6532):eabc8378. doi: 10.1126/science.abc8378. Epub 2020 Dec 23. Science. 2021. PMID: 33361116 Free PMC article.
IgG Immune Complexes Break Immune Tolerance of Human Microglia.
van der Poel M, Hoepel W, Hamann J, Huitinga I, Dunnen JD. van der Poel M, et al. Among authors: hoepel w. J Immunol. 2020 Nov 1;205(9):2511-2518. doi: 10.4049/jimmunol.2000130. Epub 2020 Sep 23. J Immunol. 2020. PMID: 32967931
High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages.
Hoepel W, Chen HJ, Geyer CE, Allahverdiyeva S, Manz XD, de Taeye SW, Aman J, Mes L, Steenhuis M, Griffith GR, Bonta PI, Brouwer PJM, Caniels TG, van der Straten K, Golebski K, Jonkers RE, Larsen MD, Linty F, Nouta J, van Roomen CPAA, van Baarle FEHP, van Drunen CM, Wolbink G, Vlaar APJ, de Bree GJ, Sanders RW, Willemsen L, Neele AE, van de Beek D, Rispens T, Wuhrer M, Bogaard HJ, van Gils MJ, Vidarsson G, de Winther M, den Dunnen J. Hoepel W, et al. Sci Transl Med. 2021 Jun 2;13(596):eabf8654. doi: 10.1126/scitranslmed.abf8654. Epub 2021 May 11. Sci Transl Med. 2021. PMID: 33979301 Free PMC article.
16 results