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Year Number of Results
2012 1
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2014 2
2015 6
2016 6
2017 9
2018 1
2019 1
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2021 4
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2024 5
2025 0

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35 results

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Page 1
Brain cell type-specific enhancer-promoter interactome maps and disease-risk association.
Nott A, Holtman IR, Coufal NG, Schlachetzki JCM, Yu M, Hu R, Han CZ, Pena M, Xiao J, Wu Y, Keulen Z, Pasillas MP, O'Connor C, Nickl CK, Schafer ST, Shen Z, Rissman RA, Brewer JB, Gosselin D, Gonda DD, Levy ML, Rosenfeld MG, McVicker G, Gage FH, Ren B, Glass CK. Nott A, et al. Among authors: holtman ir. Science. 2019 Nov 29;366(6469):1134-1139. doi: 10.1126/science.aay0793. Epub 2019 Nov 14. Science. 2019. PMID: 31727856 Free PMC article.
An environment-dependent transcriptional network specifies human microglia identity.
Gosselin D, Skola D, Coufal NG, Holtman IR, Schlachetzki JCM, Sajti E, Jaeger BN, O'Connor C, Fitzpatrick C, Pasillas MP, Pena M, Adair A, Gonda DD, Levy ML, Ransohoff RM, Gage FH, Glass CK. Gosselin D, et al. Among authors: holtman ir. Science. 2017 Jun 23;356(6344):eaal3222. doi: 10.1126/science.aal3222. Epub 2017 May 25. Science. 2017. PMID: 28546318 Free PMC article.
Diet-regulated production of PDGFcc by macrophages controls energy storage.
Cox N, Crozet L, Holtman IR, Loyher PL, Lazarov T, White JB, Mass E, Stanley ER, Elemento O, Glass CK, Geissmann F. Cox N, et al. Among authors: holtman ir. Science. 2021 Jul 2;373(6550):eabe9383. doi: 10.1126/science.abe9383. Science. 2021. PMID: 34210853 Free PMC article.
A novel microglial subset plays a key role in myelinogenesis in developing brain.
Wlodarczyk A, Holtman IR, Krueger M, Yogev N, Bruttger J, Khorooshi R, Benmamar-Badel A, de Boer-Bergsma JJ, Martin NA, Karram K, Kramer I, Boddeke EW, Waisman A, Eggen BJ, Owens T. Wlodarczyk A, et al. Among authors: holtman ir. EMBO J. 2017 Nov 15;36(22):3292-3308. doi: 10.15252/embj.201696056. Epub 2017 Sep 28. EMBO J. 2017. PMID: 28963396 Free PMC article.
Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state.
Voshart DC, Oshima T, Jiang Y, van der Linden GP, Ainslie AP, Reali Nazario L, van Buuren-Broek F, Scholma AC, van Weering HRJ, Brouwer N, Sewdihal J, Brouwer U, Coppes RP, Holtman IR, Eggen BJL, Kooistra SM, Barazzuol L. Voshart DC, et al. Among authors: holtman ir. Cell Rep. 2024 Feb 27;43(2):113764. doi: 10.1016/j.celrep.2024.113764. Epub 2024 Feb 14. Cell Rep. 2024. PMID: 38358885 Free article.
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity.
Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK. Fixsen BR, et al. Among authors: holtman ir. Nat Immunol. 2023 Jul;24(7):1188-1199. doi: 10.1038/s41590-023-01528-8. Epub 2023 Jun 15. Nat Immunol. 2023. PMID: 37322178 Free PMC article.
35 results