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Page 1
The lung microbiome regulates brain autoimmunity.
Hosang L, Canals RC, van der Flier FJ, Hollensteiner J, Daniel R, Flügel A, Odoardi F. Hosang L, et al. Nature. 2022 Mar;603(7899):138-144. doi: 10.1038/s41586-022-04427-4. Epub 2022 Feb 23. Nature. 2022. PMID: 35197636
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, Ruhwedel T, Möbius W, Sankowski R, Prinz M, Huitinga I, Sereda MW, Odoardi F, Ischebeck T, Simons M, Stadelmann-Nessler C, Edgar JM, Nave KA, Saher G. Berghoff SA, et al. Among authors: hosang l. Nat Neurosci. 2021 Jan;24(1):47-60. doi: 10.1038/s41593-020-00757-6. Epub 2020 Dec 21. Nat Neurosci. 2021. PMID: 33349711 Free PMC article.
Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice.
Berghoff SA, Spieth L, Sun T, Hosang L, Depp C, Sasmita AO, Vasileva MH, Scholz P, Zhao Y, Krueger-Burg D, Wichert S, Brown ER, Michail K, Nave KA, Bonn S, Odoardi F, Rossner M, Ischebeck T, Edgar JM, Saher G. Berghoff SA, et al. Among authors: hosang l. Cell Rep. 2021 Oct 26;37(4):109889. doi: 10.1016/j.celrep.2021.109889. Cell Rep. 2021. PMID: 34706227 Free article.
Ketogenic diet uncovers differential metabolic plasticity of brain cells.
Düking T, Spieth L, Berghoff SA, Piepkorn L, Schmidke AM, Mitkovski M, Kannaiyan N, Hosang L, Scholz P, Shaib AH, Schneider LV, Hesse D, Ruhwedel T, Sun T, Linhoff L, Trevisiol A, Köhler S, Pastor AM, Misgeld T, Sereda M, Hassouna I, Rossner MJ, Odoardi F, Ischebeck T, de Hoz L, Hirrlinger J, Jahn O, Saher G. Düking T, et al. Among authors: hosang l. Sci Adv. 2022 Sep 16;8(37):eabo7639. doi: 10.1126/sciadv.abo7639. Epub 2022 Sep 16. Sci Adv. 2022. PMID: 36112685 Free PMC article.
An opposing function of paralogs in balancing developmental synapse maturation.
Favaro PD, Huang X, Hosang L, Stodieck S, Cui L, Liu YZ, Engelhardt KA, Schmitz F, Dong Y, Löwel S, Schlüter OM. Favaro PD, et al. Among authors: hosang l. PLoS Biol. 2018 Dec 26;16(12):e2006838. doi: 10.1371/journal.pbio.2006838. eCollection 2018 Dec. PLoS Biol. 2018. PMID: 30586380 Free PMC article.
2-Methoxyestradiol-3,17-O,O-bis-sulfamate inhibits store-operated Ca2+ entry in T lymphocytes and prevents experimental autoimmune encephalomyelitis.
Hosang L, Löhndorf A, Dohle W, Rosche A, Marry S, Diercks BP, Müller-Kirschbaum LC, Flügel LT, Potter BVL, Odoardi F, Guse AH, Flügel A. Hosang L, et al. Biochim Biophys Acta Mol Cell Res. 2023 Aug;1870(6):119485. doi: 10.1016/j.bbamcr.2023.119485. Epub 2023 May 6. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 37150482 Free PMC article.
2-Methoxyestradiol and its derivatives inhibit store-operated Ca2+ entry in T cells: Identification of a new and potent inhibitor.
Löhndorf A, Hosang L, Dohle W, Odoardi F, Waschkowski SA, Rosche A, Bauche A, Winzer R, Tolosa E, Windhorst S, Marry S, Flügel A, Potter BVL, Diercks BP, Guse AH. Löhndorf A, et al. Among authors: hosang l. Biochim Biophys Acta Mol Cell Res. 2021 May;1868(6):118988. doi: 10.1016/j.bbamcr.2021.118988. Epub 2021 Feb 10. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33581218 Free PMC article.
Dietary cholesterol promotes repair of demyelinated lesions in the adult brain.
Berghoff SA, Gerndt N, Winchenbach J, Stumpf SK, Hosang L, Odoardi F, Ruhwedel T, Böhler C, Barrette B, Stassart R, Liebetanz D, Dibaj P, Möbius W, Edgar JM, Saher G. Berghoff SA, et al. Among authors: hosang l. Nat Commun. 2017 Jan 24;8:14241. doi: 10.1038/ncomms14241. Nat Commun. 2017. PMID: 28117328 Free PMC article.
Progressive maturation of silent synapses governs the duration of a critical period.
Huang X, Stodieck SK, Goetze B, Cui L, Wong MH, Wenzel C, Hosang L, Dong Y, Löwel S, Schlüter OM. Huang X, et al. Among authors: hosang l. Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3131-40. doi: 10.1073/pnas.1506488112. Epub 2015 May 26. Proc Natl Acad Sci U S A. 2015. PMID: 26015564 Free PMC article.