Pilot Randomized Controlled Trial of Interpersonal Psychotherapy for Women With Depression in Iran

Am J Psychother. 2022 Dec 1;75(4):181-185. doi: 10.1176/appi.psychotherapy.20220011. Epub 2022 Sep 2.

Abstract

Objective: Interpersonal psychotherapy (IPT) is an evidence-based psychotherapy, developed to treat major depressive disorder. The aim of this study was to conduct a preliminary investigation of the effects of IPT on depressive symptoms and quality of life among women with depression in Iran.

Methods: Adult women ages ≥18 who met DSM-5 criteria for a current major depressive episode (N=30) were randomly assigned to receive 12 weeks of individual IPT or to a waitlist control (WLC) group.

Results: Compared with women assigned to WLC, those assigned to IPT had significantly lower depression scores (F=155.1; df=1 and 26; p<0.001) and higher quality-of-life scores (F=137.5; df=1 and 26; p<0.001) posttreatment, with controls for pretreatment values.

Conclusions: Compared with WLC, IPT was associated with greater reductions in depression and improvements in quality of life, suggesting the promise of this approach for treating depression among Iranian women.

Keywords: Depressive Disorders; Interpersonal Psychotherapy; Psychotherapy; Quality of Care; Quality of Life; Women.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Depression / therapy
  • Depressive Disorder, Major* / therapy
  • Female
  • Humans
  • Infant
  • Interpersonal Psychotherapy*
  • Iran
  • Pilot Projects
  • Psychotherapy
  • Quality of Life
  • Treatment Outcome