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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 3
1972 4
1973 3
1974 2
1975 1
1976 2
1977 2
1978 2
1979 2
1980 2
1981 2
1982 5
1983 2
1984 4
1985 7
1986 5
1987 12
1988 9
1989 13
1990 16
1991 7
1992 9
1993 7
1994 11
1995 11
1996 14
1997 13
1998 17
1999 19
2000 16
2001 13
2002 18
2003 19
2004 25
2005 22
2006 24
2007 24
2008 26
2009 14
2010 24
2011 29
2012 25
2013 23
2014 25
2015 18
2016 15
2017 13
2018 9
2019 10
2020 12
2021 18
2022 10
2023 3
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Publication date

Search Results

582 results
Results by year
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Page 1
A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity.
Khan S, Zhang X, Lv D, Zhang Q, He Y, Zhang P, Liu X, Thummuri D, Yuan Y, Wiegand JS, Pei J, Zhang W, Sharma A, McCurdy CR, Kuruvilla VM, Baran N, Ferrando AA, Kim YM, Rogojina A, Houghton PJ, Huang G, Hromas R, Konopleva M, Zheng G, Zhou D. Khan S, et al. Among authors: houghton pj. Nat Med. 2019 Dec;25(12):1938-1947. doi: 10.1038/s41591-019-0668-z. Epub 2019 Dec 2. Nat Med. 2019. PMID: 31792461 Free PMC article.
The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models.
Kendsersky NM, Lindsay J, Kolb EA, Smith MA, Teicher BA, Erickson SW, Earley EJ, Mosse YP, Martinez D, Pogoriler J, Krytska K, Patel K, Groff D, Tsang M, Ghilu S, Wang Y, Seaman S, Feng Y, Croix BS, Gorlick R, Kurmasheva R, Houghton PJ, Maris JM. Kendsersky NM, et al. Among authors: houghton pj. Clin Cancer Res. 2021 May 15;27(10):2938-2946. doi: 10.1158/1078-0432.CCR-20-4221. Epub 2021 Feb 22. Clin Cancer Res. 2021. PMID: 33619171 Free PMC article.
Everolimus.
Houghton PJ. Houghton PJ. Clin Cancer Res. 2010 Mar 1;16(5):1368-72. doi: 10.1158/1078-0432.CCR-09-1314. Epub 2010 Feb 23. Clin Cancer Res. 2010. PMID: 20179227 Free PMC article. Review.
KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism.
Vaseva AV, Blake DR, Gilbert TSK, Ng S, Hostetter G, Azam SH, Ozkan-Dagliyan I, Gautam P, Bryant KL, Pearce KH, Herring LE, Han H, Graves LM, Witkiewicz AK, Knudsen ES, Pecot CV, Rashid N, Houghton PJ, Wennerberg K, Cox AD, Der CJ. Vaseva AV, et al. Among authors: houghton pj. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. doi: 10.1016/j.ccell.2018.10.001. Cancer Cell. 2018. PMID: 30423298 Free PMC article.
Pediatric oncology.
Kurmasheva RT, Houghton PJ. Kurmasheva RT, et al. Among authors: houghton pj. Curr Opin Chem Biol. 2007 Aug;11(4):424-32. doi: 10.1016/j.cbpa.2007.05.037. Epub 2007 Jul 24. Curr Opin Chem Biol. 2007. PMID: 17652007 Free PMC article. Review.
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Mack SC, Pajtler KW, Chavez L, Okonechnikov K, Bertrand KC, Wang X, Erkek S, Federation A, Song A, Lee C, Wang X, McDonald L, Morrow JJ, Saiakhova A, Sin-Chan P, Wu Q, Michaelraj KA, Miller TE, Hubert CG, Ryzhova M, Garzia L, Donovan L, Dombrowski S, Factor DC, Luu B, Valentim CLL, Gimple RC, Morton A, Kim L, Prager BC, Lee JJY, Wu X, Zuccaro J, Thompson Y, Holgado BL, Reimand J, Ke SQ, Tropper A, Lai S, Vijayarajah S, Doan S, Mahadev V, Miñan AF, Gröbner SN, Lienhard M, Zapatka M, Huang Z, Aldape KD, Carcaboso AM, Houghton PJ, Keir ST, Milde T, Witt H, Li Y, Li CJ, Bian XW, Jones DTW, Scott I, Singh SK, Huang A, Dirks PB, Bouffet E, Bradner JE, Ramaswamy V, Jabado N, Rutka JT, Northcott PA, Lupien M, Lichter P, Korshunov A, Scacheri PC, Pfister SM, Kool M, Taylor MD, Rich JN. Mack SC, et al. Among authors: houghton pj. Nature. 2018 Jan 4;553(7686):101-105. doi: 10.1038/nature25169. Epub 2017 Dec 20. Nature. 2018. PMID: 29258295 Free PMC article.
FOXO1a acts as a selective tumor suppressor in alveolar rhabdomyosarcoma.
Bois PR, Izeradjene K, Houghton PJ, Cleveland JL, Houghton JA, Grosveldz GC. Bois PR, et al. Among authors: houghton pj. J Cell Biol. 2007 May 7;177(3):563. doi: 10.1083/jcb.20050104020070420r. J Cell Biol. 2007. PMID: 17485494 Free PMC article. No abstract available.
Trastuzumab Deruxtecan, Antibody-Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium.
Hingorani P, Zhang W, Zhang Z, Xu Z, Wang WL, Roth ME, Wang Y, Gill JB, Harrison DJ, Teicher BA, Erickson SW, Gatto G, Kolb EA, Smith MA, Kurmasheva RT, Houghton PJ, Gorlick R. Hingorani P, et al. Among authors: houghton pj. Mol Cancer Ther. 2022 Aug 2;21(8):1318-1325. doi: 10.1158/1535-7163.MCT-21-0758. Mol Cancer Ther. 2022. PMID: 35657346
Acetylcholinesterase inhibitors from plants.
Mukherjee PK, Kumar V, Mal M, Houghton PJ. Mukherjee PK, et al. Among authors: houghton pj. Phytomedicine. 2007 Apr;14(4):289-300. doi: 10.1016/j.phymed.2007.02.002. Epub 2007 Mar 7. Phytomedicine. 2007. PMID: 17346955 Review.
582 results