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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 1
1989 2
1990 2
1991 1
1992 1
1994 2
1995 2
1996 1
1998 4
1999 4
2000 5
2001 4
2002 5
2003 2
2004 7
2005 2
2006 2
2007 3
2008 7
2009 6
2010 5
2011 3
2012 5
2013 5
2014 1
2015 1
2016 4
2017 8
2018 7
2019 6
2020 3
2021 5
2022 0
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108 results
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Page 1
ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies.
Zammarchi F, Corbett S, Adams L, Tyrer PC, Kiakos K, Janghra N, Marafioti T, Britten CE, Havenith CEG, Chivers S, D'Hooge F, Williams DG, Tiberghien A, Howard PW, Hartley JA, van Berkel PH. Zammarchi F, et al. Among authors: howard pw. Blood. 2018 Mar 8;131(10):1094-1105. doi: 10.1182/blood-2017-10-813493. Epub 2018 Jan 3. Blood. 2018. PMID: 29298756 Free article.
Antibody-drug conjugates - a perfect synergy.
Adair JR, Howard PW, Hartley JA, Williams DG, Chester KA. Adair JR, et al. Among authors: howard pw. Expert Opin Biol Ther. 2012 Sep;12(9):1191-206. doi: 10.1517/14712598.2012.693473. Epub 2012 Jun 1. Expert Opin Biol Ther. 2012. PMID: 22650648 Review.
Potentiation of PBD Dimers by Lipophilicity Manipulation.
Cailleau T, Adams LR, Arora N, Kang GD, Masterson L, Patel N, Hartley JA, Mao S, Harper J, Howard PW. Cailleau T, et al. Among authors: howard pw. Curr Top Med Chem. 2019;19(9):741-752. doi: 10.2174/1568026619666190401112517. Curr Top Med Chem. 2019. PMID: 30931859
Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR.
Mao S, Chaerkady R, Yu W, D'Angelo G, Garcia A, Chen H, Barrett AM, Phipps S, Fleming R, Hess S, Koopmann JO, Dimasi N, Wilson S, Pugh K, Cook K, Masterson LA, Gao C, Wu H, Herbst R, Howard PW, Tice DA, Cobbold M, Harper J. Mao S, et al. Among authors: howard pw. Mol Cancer Ther. 2021 Mar;20(3):541-552. doi: 10.1158/1535-7163.MCT-20-0351. Mol Cancer Ther. 2021. PMID: 33653945 Free article.
Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers.
Gregson SJ, Barrett AM, Patel NV, Kang GD, Schiavone D, Sult E, Barry CS, Vijayakrishnan B, Adams LR, Masterson LA, D'Hooge F, Snaith M, Harper J, Hartley JA, Howard PW. Gregson SJ, et al. Among authors: howard pw. Eur J Med Chem. 2019 Oct 1;179:591-607. doi: 10.1016/j.ejmech.2019.06.044. Epub 2019 Jun 18. Eur J Med Chem. 2019. PMID: 31279293
108 results