Huehls AM[au] - Search Results

Year	Number of Results
2006	1
2007	1
2011	2
2012	1
2013	1
2014	1
2015	2
2016	1
2017	1
2019	1
2021	2
2022	2
2023	0

1

Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma.

Kanakkanthara A, Hou X, Ekstrom TL, Zanfagnin V, Huehls AM, Kelly RL, Ding H, Larson MC, Vasmatzis G, Oberg AL, Kaufmann SH, Mansfield AS, Weroha SJ, Karnitz LM. Kanakkanthara A, et al. Among authors: huehls am. Cancer Res. 2022 Jan 15;82(2):307-319. doi: 10.1158/0008-5472.CAN-21-0732. Epub 2021 Nov 22. Cancer Res. 2022. PMID: 34810199 Free PMC article.

2

Bispecific T-cell engagers for cancer immunotherapy.

Huehls AM, Coupet TA, Sentman CL. Huehls AM, et al. Immunol Cell Biol. 2015 Mar;93(3):290-6. doi: 10.1038/icb.2014.93. Epub 2014 Nov 4. Immunol Cell Biol. 2015. PMID: 25367186 Free PMC article. Review.

3

Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress.

Kelly RL, Huehls AM, Venkatachalam A, Huntoon CJ, Machida YJ, Karnitz LM. Kelly RL, et al. Among authors: huehls am. J Biol Chem. 2022 Apr;298(4):101777. doi: 10.1016/j.jbc.2022.101777. Epub 2022 Feb 26. J Biol Chem. 2022. PMID: 35231445 Free PMC article.

4

VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases.

Ekstrom TL, Pathoulas NM, Huehls AM, Kanakkanthara A, Karnitz LM. Ekstrom TL, et al. Among authors: huehls am. Mol Cancer Ther. 2021 Sep;20(9):1561-1571. doi: 10.1158/1535-7163.MCT-20-1099. Epub 2021 Jun 17. Mol Cancer Ther. 2021. PMID: 34224364 Free PMC article.

5

Effect of CHK1 Inhibition on CPX-351 Cytotoxicity in vitro and ex vivo.

Vincelette ND, Ding H, Huehls AM, Flatten KS, Kelly RL, Kohorst MA, Webster J, Hess AD, Pratz KW, Karnitz LM, Kaufmann SH. Vincelette ND, et al. Among authors: huehls am. Sci Rep. 2019 Mar 5;9(1):3617. doi: 10.1038/s41598-019-40218-0. Sci Rep. 2019. PMID: 30837643 Free PMC article.

6

NKG2D Ligand-Targeted Bispecific T-Cell Engagers Lead to Robust Antitumor Activity against Diverse Human Tumors.

Godbersen C, Coupet TA, Huehls AM, Zhang T, Battles MB, Fisher JL, Ernstoff MS, Sentman CL. Godbersen C, et al. Among authors: huehls am. Mol Cancer Ther. 2017 Jul;16(7):1335-1346. doi: 10.1158/1535-7163.MCT-16-0846. Epub 2017 May 12. Mol Cancer Ther. 2017. PMID: 28500232 Free PMC article.

7

Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.

Huehls AM, Wagner JM, Huntoon CJ, Geng L, Erlichman C, Patel AG, Kaufmann SH, Karnitz LM. Huehls AM, et al. Cancer Res. 2011 Jul 15;71(14):4944-54. doi: 10.1158/0008-5472.CAN-11-0814. Epub 2011 May 25. Cancer Res. 2011. PMID: 21613406 Free PMC article.

8

ATR inhibition broadly sensitizes ovarian cancer cells to chemotherapy independent of BRCA status.

Huntoon CJ, Flatten KS, Wahner Hendrickson AE, Huehls AM, Sutor SL, Kaufmann SH, Karnitz LM. Huntoon CJ, et al. Among authors: huehls am. Cancer Res. 2013 Jun 15;73(12):3683-91. doi: 10.1158/0008-5472.CAN-13-0110. Epub 2013 Apr 2. Cancer Res. 2013. PMID: 23548269 Free PMC article.

9

Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous Recombination.

Huehls AM, Huntoon CJ, Joshi PM, Baehr CA, Wagner JM, Wang X, Lee MY, Karnitz LM. Huehls AM, et al. Mol Pharmacol. 2016 Jan;89(1):53-62. doi: 10.1124/mol.115.100164. Epub 2015 Oct 22. Mol Pharmacol. 2016. PMID: 26494862 Free PMC article.

10

Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.

Geng L, Huehls AM, Wagner JM, Huntoon CJ, Karnitz LM. Geng L, et al. Among authors: huehls am. PLoS One. 2011;6(12):e28862. doi: 10.1371/journal.pone.0028862. Epub 2011 Dec 15. PLoS One. 2011. PMID: 22194930 Free PMC article.

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