Hughes JR[au] - Search Results

Year	Number of Results
1946	5
1947	10
1948	5
1949	3
1950	3
1951	2
1952	4
1953	2
1954	4
1955	4
1956	6
1957	5
1958	2
1959	5
1960	7
1961	2
1962	5
1963	5
1964	4
1965	10
1966	12
1967	3
1968	7
1969	11
1970	12
1971	7
1972	11
1973	12
1974	7
1975	11
1976	14
1977	7
1978	5
1979	9
1980	10
1981	12
1982	7
1983	15
1984	26
1985	29
1986	22
1987	27
1988	23
1989	27
1990	33
1991	35
1992	40
1993	34
1994	39
1995	37
1996	33
1997	24
1998	21
1999	22
2000	26
2001	19
2002	13
2003	19
2004	24
2005	19
2006	16
2007	22
2008	22
2009	32
2010	24
2011	21
2012	18
2013	19
2014	15
2015	20
2016	28
2017	33
2018	22
2019	24
2020	28
2021	20

1

Hughes JR, Stead LF, Hartmann-Boyce J, Cahill K, Lancaster T. Hughes JR, et al. Cochrane Database Syst Rev. 2014 Jan 8;2014(1):CD000031. doi: 10.1002/14651858.CD000031.pub4. Cochrane Database Syst Rev. 2014. PMID: 24402784 Free PMC article. Updated. Review.

2

Loss of Extreme Long-Range Enhancers in Human Neural Crest Drives a Craniofacial Disorder.

Long HK, Osterwalder M, Welsh IC, Hansen K, Davies JOJ, Liu YE, Koska M, Adams AT, Aho R, Arora N, Ikeda K, Williams RM, Sauka-Spengler T, Porteus MH, Mohun T, Dickel DE, Swigut T, Hughes JR, Higgs DR, Visel A, Selleri L, Wysocka J. Long HK, et al. Among authors: hughes jr. Cell Stem Cell. 2020 Nov 5;27(5):765-783.e14. doi: 10.1016/j.stem.2020.09.001. Epub 2020 Sep 28. Cell Stem Cell. 2020. PMID: 32991838 Free PMC article.

3

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA. Godfrey L, et al. Among authors: hughes jr. Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3. Nat Commun. 2019. PMID: 31243293 Free PMC article.

4

A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition.

Traxler EA, Yao Y, Wang YD, Woodard KJ, Kurita R, Nakamura Y, Hughes JR, Hardison RC, Blobel GA, Li C, Weiss MJ. Traxler EA, et al. Among authors: hughes jr. Nat Med. 2016 Sep;22(9):987-90. doi: 10.1038/nm.4170. Epub 2016 Aug 15. Nat Med. 2016. PMID: 27525524 Free PMC article.

5

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin.

Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H. Lim PJ, et al. Among authors: hughes jr. Nat Metab. 2019 May;1(5):519-531. doi: 10.1038/s42255-019-0063-6. Epub 2019 May 13. Nat Metab. 2019. PMID: 31276102 Free PMC article.

6

How best to identify chromosomal interactions: a comparison of approaches.

Davies JO, Oudelaar AM, Higgs DR, Hughes JR. Davies JO, et al. Among authors: hughes jr. Nat Methods. 2017 Jan 31;14(2):125-134. doi: 10.1038/nmeth.4146. Nat Methods. 2017. PMID: 28139673 Review.

7

Genetic dissection of the α-globin super-enhancer in vivo.

Hay D, Hughes JR, Babbs C, Davies JOJ, Graham BJ, Hanssen L, Kassouf MT, Marieke Oudelaar AM, Sharpe JA, Suciu MC, Telenius J, Williams R, Rode C, Li PS, Pennacchio LA, Sloane-Stanley JA, Ayyub H, Butler S, Sauka-Spengler T, Gibbons RJ, Smith AJH, Wood WG, Higgs DR. Hay D, et al. Among authors: hughes jr. Nat Genet. 2016 Aug;48(8):895-903. doi: 10.1038/ng.3605. Epub 2016 Jul 4. Nat Genet. 2016. PMID: 27376235 Free PMC article.

8

Multiplexed analysis of chromosome conformation at vastly improved sensitivity.

Davies JO, Telenius JM, McGowan SJ, Roberts NA, Taylor S, Higgs DR, Hughes JR. Davies JO, et al. Among authors: hughes jr. Nat Methods. 2016 Jan;13(1):74-80. doi: 10.1038/nmeth.3664. Epub 2015 Nov 23. Nat Methods. 2016. PMID: 26595209 Free PMC article.

9

Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia.

Mettananda S, Fisher CA, Hay D, Badat M, Quek L, Clark K, Hublitz P, Downes D, Kerry J, Gosden M, Telenius J, Sloane-Stanley JA, Faustino P, Coelho A, Doondeea J, Usukhbayar B, Sopp P, Sharpe JA, Hughes JR, Vyas P, Gibbons RJ, Higgs DR. Mettananda S, et al. Among authors: hughes jr. Nat Commun. 2017 Sep 4;8(1):424. doi: 10.1038/s41467-017-00479-7. Nat Commun. 2017. PMID: 28871148 Free PMC article.

10

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma.

Yao X, Tan J, Lim KJ, Koh J, Ooi WF, Li Z, Huang D, Xing M, Chan YS, Qu JZ, Tay ST, Wijaya G, Lam YN, Hong JH, Lee-Lim AP, Guan P, Ng MSW, He CZ, Lin JS, Nandi T, Qamra A, Xu C, Myint SS, Davies JOJ, Goh JY, Loh G, Tan BC, Rozen SG, Yu Q, Tan IBH, Cheng CWS, Li S, Chang KTE, Tan PH, Silver DL, Lezhava A, Steger G, Hughes JR, Teh BT, Tan P. Yao X, et al. Among authors: hughes jr. Cancer Discov. 2017 Nov;7(11):1284-1305. doi: 10.1158/2159-8290.CD-17-0375. Epub 2017 Sep 11. Cancer Discov. 2017. PMID: 28893800 Free article.

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