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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2007 1
2008 1
2009 3
2010 4
2011 1
2012 1
2013 3
2014 4
2015 1
2016 1
2017 4
2018 3
2019 3
2020 4
2021 10
2022 5
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44 results
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Page 1
An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19.
Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Among authors: hurst bl. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479
Trivalent Subunit Vaccine Candidates for COVID-19 and Their Delivery Devices.
Ortega-Rivera OA, Shin MD, Chen A, Beiss V, Moreno-Gonzalez MA, Lopez-Ramirez MA, Reynoso M, Wang H, Hurst BL, Wang J, Pokorski JK, Steinmetz NF. Ortega-Rivera OA, et al. Among authors: hurst bl. J Am Chem Soc. 2021 Sep 15;143(36):14748-14765. doi: 10.1021/jacs.1c06600. Epub 2021 Sep 7. J Am Chem Soc. 2021. PMID: 34490778 Free PMC article.
Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice.
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, LeeMontiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, Dickmander R, Baric R, Pearce KH, Cunha FQ, Alves-Filho JC, Cunha TM, Ekins S. Puhl AC, et al. Among authors: hurst bl. bioRxiv. 2021 Dec 20:2021.12.16.472155. doi: 10.1101/2021.12.16.472155. Preprint. bioRxiv. 2021. PMID: 34981062 Free PMC article.
Vandetanib Blocks the Cytokine Storm in SARS-CoV-2-Infected Mice.
Puhl AC, Gomes GF, Damasceno S, Fritch EJ, Levi JA, Johnson NJ, Scholle F, Premkumar L, Hurst BL, Lee-Montiel F, Veras FP, Batah SS, Fabro AT, Moorman NJ, Yount BL, Dickmander RJ, Baric RS, Pearce KH, Cunha FQ, Alves-Filho JC, Cunha TM, Ekins S. Puhl AC, et al. Among authors: hurst bl. ACS Omega. 2022 Aug 29;7(36):31935-31944. doi: 10.1021/acsomega.2c02794. eCollection 2022 Sep 13. ACS Omega. 2022. PMID: 36097511 Free PMC article.
A Clinical-Stage Cysteine Protease Inhibitor blocks SARS-CoV-2 Infection of Human and Monkey Cells.
Mellott DM, Tseng CT, Drelich A, Fajtová P, Chenna BC, Kostomiris DH, Hsu J, Zhu J, Taylor ZW, Kocurek KI, Tat V, Katzfuss A, Li L, Giardini MA, Skinner D, Hirata K, Yoon MC, Beck S, Carlin AF, Clark AE, Beretta L, Maneval D, Hook V, Frueh F, Hurst BL, Wang H, Raushel FM, O'Donoghue AJ, de Siqueira-Neto JL, Meek TD, McKerrow JH. Mellott DM, et al. Among authors: hurst bl. ACS Chem Biol. 2021 Apr 16;16(4):642-650. doi: 10.1021/acschembio.0c00875. Epub 2021 Mar 31. ACS Chem Biol. 2021. PMID: 33787221 Free PMC article.
High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of viral activity.
Choi R, Zhou M, Shek R, Wilson JW, Tillery L, Craig JK, Salukhe IA, Hickson SE, Kumar N, James RM, Buchko GW, Wu R, Huff S, Nguyen TT, Hurst BL, Cherry S, Barrett LK, Hyde JL, Van Voorhis WC. Choi R, et al. Among authors: hurst bl. PLoS One. 2021 Apr 22;16(4):e0250019. doi: 10.1371/journal.pone.0250019. eCollection 2021. PLoS One. 2021. PMID: 33886614 Free PMC article.
44 results