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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 2
1992 2
1995 2
1996 1
1997 1
1998 1
1999 1
2000 1
2001 4
2003 3
2004 2
2005 4
2006 3
2007 2
2008 1
2010 4
2011 1
2013 3
2014 1
2015 1
2018 1
2022 1
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38 results
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Page 1
Discovery of Oxazoline Enhancers of Cellular Progranulin Release.
Peng X, Lanter JC, Y-P Chen A, Brand MA, Wozniak MK, Hoekman S, Longin O, Regeling H, Zonneveld W, P L Bell R, Koenig G, Hurst RS, Blain JF, Burnett DA. Peng X, et al. Among authors: hurst rs. Bioorg Med Chem Lett. 2022 Nov 8:129048. doi: 10.1016/j.bmcl.2022.129048. Online ahead of print. Bioorg Med Chem Lett. 2022. PMID: 36368496
The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242).
Shaffer CL, Patel NC, Schwarz J, Scialis RJ, Wei Y, Hou XJ, Xie L, Karki K, Bryce DK, Osgood SM, Hoffmann WE, Lazzaro JT, Chang C, McGinnis DF, Lotarski SM, Liu J, Obach RS, Weber ML, Chen L, Zasadny KR, Seymour PA, Schmidt CJ, Hajós M, Hurst RS, Pandit J, O'Donnell CJ. Shaffer CL, et al. Among authors: hurst rs. J Med Chem. 2015 May 28;58(10):4291-308. doi: 10.1021/acs.jmedchem.5b00300. Epub 2015 May 14. J Med Chem. 2015. PMID: 25905800
Discovery and characterization of a novel dihydroisoxazole class of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiators.
Patel NC, Schwarz J, Hou XJ, Hoover DJ, Xie L, Fliri AJ, Gallaschun RJ, Lazzaro JT, Bryce DK, Hoffmann WE, Hanks AN, McGinnis D, Marr ES, Gazard JL, Hajós M, Scialis RJ, Hurst RS, Shaffer CL, Pandit J, O'Donnell CJ. Patel NC, et al. Among authors: hurst rs. J Med Chem. 2013 Nov 27;56(22):9180-91. doi: 10.1021/jm401274b. Epub 2013 Nov 11. J Med Chem. 2013. PMID: 24215237
Dopamine D4 receptor-deficient mice display cortical hyperexcitability.
Rubinstein M, Cepeda C, Hurst RS, Flores-Hernandez J, Ariano MA, Falzone TL, Kozell LB, Meshul CK, Bunzow JR, Low MJ, Levine MS, Grandy DK. Rubinstein M, et al. Among authors: hurst rs. J Neurosci. 2001 Jun 1;21(11):3756-63. doi: 10.1523/JNEUROSCI.21-11-03756.2001. J Neurosci. 2001. PMID: 11356863 Free PMC article.
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity.
Acker BA, Jacobsen EJ, Rogers BN, Wishka DG, Reitz SC, Piotrowski DW, Myers JK, Wolfe ML, Groppi VE, Thornburgh BA, Tinholt PM, Walters RR, Olson BA, Fitzgerald L, Staton BA, Raub TJ, Krause M, Li KS, Hoffmann WE, Hajos M, Hurst RS, Walker DP. Acker BA, et al. Among authors: hurst rs. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3611-5. doi: 10.1016/j.bmcl.2008.04.070. Epub 2008 May 1. Bioorg Med Chem Lett. 2008. PMID: 18490160
38 results